 Phosphofructokinase-1, Muscle Type
"Phosphofructokinase-1, Muscle Type" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
| Descriptor ID |
D025203
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| MeSH Number(s) |
D08.811.913.696.620.225.850.500.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphofructokinase-1, Muscle Type".
Below are MeSH descriptors whose meaning is more specific than "Phosphofructokinase-1, Muscle Type".
This graph shows the total number of publications written about "Phosphofructokinase-1, Muscle Type" by people in this website by year, and whether "Phosphofructokinase-1, Muscle Type" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphofructokinase-1, Muscle Type" by people in Profiles.
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Keildson S, Fadista J, Ladenvall C, Hedman ?K, Elgzyri T, Small KS, Grundberg E, Nica AC, Glass D, Richards JB, Barrett A, Nisbet J, Zheng HF, R?nn T, Str?m K, Eriksson KF, Prokopenko I, Spector TD, Dermitzakis ET, Deloukas P, McCarthy MI, Rung J, Groop L, Franks PW, Lindgren CM, Hansson O. Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity. Diabetes. 2014 Mar; 63(3):1154-65.
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