Protein Structure, Tertiary
"Protein Structure, Tertiary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Descriptor ID |
D017434
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MeSH Number(s) |
G02.111.570.820.709.610
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Concept/Terms |
Protein Structure, Tertiary- Protein Structure, Tertiary
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domains
- Domain, Protein
- Domains, Protein
- Protein Domain
- Tertiary Protein Structure
- Protein Structures, Tertiary
- Tertiary Protein Structures
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Below are MeSH descriptors whose meaning is more general than "Protein Structure, Tertiary".
Below are MeSH descriptors whose meaning is more specific than "Protein Structure, Tertiary".
This graph shows the total number of publications written about "Protein Structure, Tertiary" by people in this website by year, and whether "Protein Structure, Tertiary" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2002 | 0 | 2 | 2 | 2005 | 0 | 1 | 1 | 2007 | 0 | 3 | 3 | 2008 | 0 | 2 | 2 | 2009 | 0 | 1 | 1 | 2011 | 0 | 2 | 2 | 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protein Structure, Tertiary" by people in Profiles.
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Bradley T, Cook ME, Blanchette M. SR proteins control a complex network of RNA-processing events. RNA. 2015 Jan; 21(1):75-92.
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Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, Gleason CE, Murphy JM, Rosenberg BR, Teegan L, Takacs CN, Botero S, Belote R, Germer S, Emde AK, Vacic V, Bhanot U, LaQuaglia MP, Simon SM. Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma. Science. 2014 Feb 28; 343(6174):1010-4.
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Austgen K, Johnson ET, Park TJ, Curran T, Oakes SA. The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress. Nat Cell Biol. 2011 Dec 18; 14(1):87-92.
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Farrow EG, Yu X, Summers LJ, Davis SI, Fleet JC, Allen MR, Robling AG, Stayrook KR, Jideonwo V, Magers MJ, Garringer HJ, Vidal R, Chan RJ, Goodwin CB, Hui SL, Peacock M, White KE. Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):E1146-55.
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Guest EM, Neville KA, Hoyer JD, Safo MK, Garg U, Saunders CJ, Abdulmalik O, Zwick DL. Hb Lake Tapawingo [a46(CE4)Phe?Ser; HBA2:c.140T>C]: a new unstable a chain hemoglobin variant associated with low systemic arterial saturation. Hemoglobin. 2011; 35(4):411-6.
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Singh AK, Yadav VN, Pyaram K, Mullick J, Sahu A. Mapping of functional domains in herpesvirus saimiri complement control protein homolog: complement control protein domain 2 is the smallest structural unit displaying cofactor and decay-accelerating activities. J Virol. 2009 Oct; 83(19):10299-304.
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Dutta D, Ray S, Vivian JL, Paul S. Activation of the VEGFR1 chromatin domain: an angiogenic signal-ETS1/HIF-2alpha regulatory axis. J Biol Chem. 2008 Sep 12; 283(37):25404-25413.
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Ji Y, Snyder EM, Fridley BL, Salavaggione OE, Moon I, Batzler A, Yee VC, Schaid DJ, Joyner MJ, Johnson BD, Weinshilboum RM. Human phenylethanolamine N-methyltransferase genetic polymorphisms and exercise-induced epinephrine release. Physiol Genomics. 2008 May 13; 33(3):323-32.
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Farrow EG, Davis SI, Ward LM, White KE. The role of DMP1 in autosomal recessive hypophosphatemic rickets. J Musculoskelet Neuronal Interact. 2007 Oct-Dec; 7(4):310-2.
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Iwakuma T, Lozano G. Crippling p53 activities via knock-in mutations in mouse models. Oncogene. 2007 Apr 02; 26(15):2177-84.
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