 Granulocyte-Macrophage Colony-Stimulating Factor
"Granulocyte-Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
| Descriptor ID |
D016178
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| MeSH Number(s) |
D12.644.276.374.410.240.375 D12.776.395.240.300 D12.776.467.374.410.240.375 D23.529.374.410.240.375
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| Concept/Terms |
Granulocyte-Macrophage Colony-Stimulating Factor- Granulocyte-Macrophage Colony-Stimulating Factor
- Granulocyte Macrophage Colony Stimulating Factor
- CSF-2
- Tumor-Cell Human GM Colony-Stimulating Factor
- Tumor Cell Human GM Colony Stimulating Factor
- GM-CSF
- Histamine-Producing Cell-Stimulating Factor
- Cell-Stimulating Factor, Histamine-Producing
- Histamine Producing Cell Stimulating Factor
- TC-GM-CSF
- Colony-Stimulating Factor, Granulocyte-Macrophage
- Colony Stimulating Factor, Granulocyte Macrophage
- CSF-GM
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Below are MeSH descriptors whose meaning is more general than "Granulocyte-Macrophage Colony-Stimulating Factor".
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This graph shows the total number of publications written about "Granulocyte-Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Granulocyte-Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Granulocyte-Macrophage Colony-Stimulating Factor" by people in Profiles.
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Narayanan P, Man TK, Gerbing RB, Ries R, Stevens AM, Wang YC, Long X, Gamis AS, Cooper T, Meshinchi S, Alonzo TA, Redell MS. Aberrantly low STAT3 and STAT5 responses are associated with poor outcome and an inflammatory gene expression signature in pediatric acute myeloid leukemia. Clin Transl Oncol. 2021 Oct; 23(10):2141-2154.
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