 Genes, Tumor Suppressor
"Genes, Tumor Suppressor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
| Descriptor ID |
D016147
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| MeSH Number(s) |
G05.360.340.024.340.375.249 G05.360.340.024.340.415.400
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| Concept/Terms |
Genes, Tumor Suppressor- Genes, Tumor Suppressor
- Gene, Tumor Suppressor
- Tumor Suppressor Gene
- Antioncogenes
- Antioncogene
- Emerogenes
- Emerogene
- Genes, Onco-Suppressor
- Gene, Onco-Suppressor
- Genes, Onco Suppressor
- Onco-Suppressor Gene
- Onco-Suppressor Genes
- Cancer Suppressor Genes
- Cancer Suppressor Gene
- Gene, Cancer Suppressor
- Suppressor Gene, Cancer
- Suppressor Genes, Cancer
- Oncogenes, Recessive
- Oncogene, Recessive
- Recessive Oncogene
- Recessive Oncogenes
- Anti-Oncogenes
- Anti Oncogenes
- Anti-Oncogene
- Tumor Suppressing Genes
- Gene, Tumor Suppressing
- Genes, Tumor Suppressing
- Tumor Suppressing Gene
- Genes, Cancer Suppressor
- Tumor Suppressor Genes
Metastasis Suppressor Genes- Metastasis Suppressor Genes
- Gene, Metastasis Suppressor
- Metastasis Suppressor Gene
- Suppressor Gene, Metastasis
- Suppressor Genes, Metastasis
- Genes, Metastasis Suppressor
Growth Suppressor Genes- Growth Suppressor Genes
- Gene, Growth Suppressor
- Growth Suppressor Gene
- Suppressor Gene, Growth
- Suppressor Genes, Growth
- Genes, Growth Suppressor
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Below are MeSH descriptors whose meaning is more general than "Genes, Tumor Suppressor".
Below are MeSH descriptors whose meaning is more specific than "Genes, Tumor Suppressor".
- Genes, Tumor Suppressor
- Genes, APC
- Genes, BRCA1
- Genes, BRCA2
- Genes, DCC
- Genes, MCC
- Genes, Neurofibromatosis 1
- Genes, Neurofibromatosis 2
- Genes, p16
- Genes, p53
- Genes, Retinoblastoma
- Genes, Wilms Tumor
This graph shows the total number of publications written about "Genes, Tumor Suppressor" by people in this website by year, and whether "Genes, Tumor Suppressor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Genes, Tumor Suppressor" by people in Profiles.
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Marinaccio C, Suraneni P, Celik H, Volk A, Wen QJ, Ling T, Bulic M, Lasho T, Koche RP, Famulare CA, Farnoud N, Stein B, Schieber M, Gurbuxani S, Root DE, Younger ST, Hoffman R, Gangat N, Ntziachristos P, Chandel NS, Levine RL, Rampal RK, Challen GA, Tefferi A, Crispino JD. LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms. Cancer Discov. 2021 06; 11(6):1398-1410.
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Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG. Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival. Cancer Discov. 2019 02; 9(2):230-247.
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Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE. The genetic landscape of the childhood cancer medulloblastoma. Science. 2011 Jan 28; 331(6016):435-9.
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Odvody J, Vincent T, Arrate MP, Grieb B, Wang S, Garriga J, Lozano G, Iwakuma T, Haines DS, Eischen CM. A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis. Oncogene. 2010 Jun 03; 29(22):3287-96.
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Lee Y, Kawagoe R, Sasai K, Li Y, Russell HR, Curran T, McKinnon PJ. Loss of suppressor-of-fused function promotes tumorigenesis. Oncogene. 2007 Sep 27; 26(44):6442-7.
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Ward IM, Difilippantonio S, Minn K, Mueller MD, Molina JR, Yu X, Frisk CS, Ried T, Nussenzweig A, Chen J. 53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice. Mol Cell Biol. 2005 Nov; 25(22):10079-86.
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Butler MG, Dasouki MJ, Zhou XP, Talebizadeh Z, Brown M, Takahashi TN, Miles JH, Wang CH, Stratton R, Pilarski R, Eng C. Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations. J Med Genet. 2005 Apr; 42(4):318-21.
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Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM, Valentin-Vega YA, Terzian T, Caldwell LC, Strong LC, El-Naggar AK, Lozano G. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell. 2004 Dec 17; 119(6):861-72.
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Yun M, Keshvara L, Park CG, Zhang YM, Dickerson JB, Zheng J, Rock CO, Curran T, Park HW. Crystal structures of the Dab homology domains of mouse disabled 1 and 2. J Biol Chem. 2003 Sep 19; 278(38):36572-81.
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