 Arylsulfotransferase
"Arylsulfotransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
| Descriptor ID |
D015239
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| MeSH Number(s) |
D08.811.913.817.400.300
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| Concept/Terms |
Arylsulfotransferase- Arylsulfotransferase
- Aryl Sulfotransferase
- Sulfotransferase, Aryl
- Phenolsulfokinase
- Phenol Sulfotransferase
- Sulfotransferase, Phenol
- Sulfokinase
- Phenol Sulfokinase
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Below are MeSH descriptors whose meaning is more general than "Arylsulfotransferase".
Below are MeSH descriptors whose meaning is more specific than "Arylsulfotransferase".
This graph shows the total number of publications written about "Arylsulfotransferase" by people in this website by year, and whether "Arylsulfotransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Arylsulfotransferase" by people in Profiles.
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Gaedigk A, Twist GP, Leeder JS. CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR. Pharmacogenomics. 2012 Jan; 13(1):91-111.
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Gaedigk A, Gaedigk R, Leeder JS. UGT2B17 and SULT1A1 gene copy number variation (CNV) detection by LabChip microfluidic technology. Clin Chem Lab Med. 2010 May; 48(5):627-33.
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Bidwell LM, McManus ME, Gaedigk A, Kakuta Y, Negishi M, Pedersen L, Martin JL. Crystal structure of human catecholamine sulfotransferase. J Mol Biol. 1999 Oct 29; 293(3):521-30.
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Brix LA, Duggleby RG, Gaedigk A, McManus ME. Structural characterization of human aryl sulphotransferases. Biochem J. 1999 Jan 15; 337 ( Pt 2):337-43.
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Bidwell LM, Gillam EM, Gaedigk A, Zhu X, Grant D, McManus ME. Bacterial expression of two human aryl sulfotransferases. Chem Biol Interact. 1998 Feb 20; 109(1-3):137-41.
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Gaedigk A, Beatty BG, Grant DM. Cloning, structural organization, and chromosomal mapping of the human phenol sulfotransferase STP2 gene. Genomics. 1997 Mar 01; 40(2):242-6.
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