Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.

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Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.

Pearce RE, Gotschall RR, Kearns GL, Leeder JS. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms. Drug Metab Dispos. 2001 Dec; 29(12):1548-54.

View in: PubMed

subject areas

Anti-Ulcer Agents
Aryl Hydrocarbon Hydroxylases
Biotransformation
Chromatography, High Pressure Liquid
Cisapride
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System
Humans
In Vitro Techniques
Isoenzymes
Male
Mass Spectrometry
Oxidoreductases, N-Demethylating
Stereoisomerism

authors with profiles

J. Steven Leeder