Nucleic Acid Hybridization
"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Descriptor ID |
D009693
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MeSH Number(s) |
E05.393.661 G02.111.087.620 G02.149.115.620
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Concept/Terms |
Nucleic Acid Hybridization- Nucleic Acid Hybridization
- Acid Hybridization, Nucleic
- Acid Hybridizations, Nucleic
- Hybridization, Nucleic Acid
- Hybridizations, Nucleic Acid
- Nucleic Acid Hybridizations
Genomic Hybridization- Genomic Hybridization
- Genomic Hybridizations
- Hybridization, Genomic
- Hybridizations, Genomic
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Hybridization".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Hybridization".
This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in this website by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleic Acid Hybridization" by people in Profiles.
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Zhang P, Crow J, Lella D, Zhou X, Samuel G, Godwin AK, Zeng Y. Ultrasensitive quantification of tumor mRNAs in extracellular vesicles with an integrated microfluidic digital analysis chip. Lab Chip. 2018 12 04; 18(24):3790-3801.
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Butler MG, Fischer W, Kibiryeva N, Bittel DC. Array comparative genomic hybridization (aCGH) analysis in Prader-Willi syndrome. Am J Med Genet A. 2008 Apr 01; 146A(7):854-60.
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Bittel DC, Kibiryeva N, Dasouki M, Knoll JH, Butler MG. A 9-year-old male with a duplication of chromosome 3p25.3p26.2: clinical report and gene expression analysis. Am J Med Genet A. 2006 Mar 15; 140(6):573-9.
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Pastinen T, Kurg A, Metspalu A, Peltonen L, Syv?nen AC. Minisequencing: a specific tool for DNA analysis and diagnostics on oligonucleotide arrays. Genome Res. 1997 Jun; 7(6):606-14.
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Yeowell HN, McClellan-Green PD, Negishi M, Goldstein JA. Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. Biochemistry. 1990 Jan 23; 29(3):713-8.
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Sonnenberg JL, Mitchelmore C, Macgregor-Leon PF, Hempstead J, Morgan JI, Curran T. Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain. J Neurosci Res. 1989 Sep; 24(1):72-80.
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