 Leukemia, Megakaryoblastic, Acute
"Leukemia, Megakaryoblastic, Acute" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common.
| Descriptor ID |
D007947
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| MeSH Number(s) |
C04.557.337.539.275.450
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| Concept/Terms |
Leukemia, Megakaryoblastic, Acute- Leukemia, Megakaryoblastic, Acute
- Myeloid Leukemia, Acute, M7
- Megakaryocytic Leukemia
- Leukemia, Megakaryocytic, Acute
- Megakaryoblastic Leukemia, Acute
- Acute Megakaryoblastic Leukemia
- Acute Megakaryoblastic Leukemias
- Leukemia, Acute Megakaryoblastic
- Leukemias, Acute Megakaryoblastic
- Megakaryoblastic Leukemias, Acute
- Leukemia, Megakaryocytic
- Leukemias, Megakaryocytic
- Megakaryocytic Leukemias
- Leukemia, Myeloid, Acute, M7
- Megakaryocytic Leukemia, Acute
- Acute Megakaryocytic Leukemia
- Acute Megakaryocytic Leukemias
- Leukemia, Acute Megakaryocytic
- Leukemias, Acute Megakaryocytic
- Megakaryocytic Leukemias, Acute
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Megakaryoblastic, Acute".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Megakaryoblastic, Acute".
This graph shows the total number of publications written about "Leukemia, Megakaryoblastic, Acute" by people in this website by year, and whether "Leukemia, Megakaryoblastic, Acute" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukemia, Megakaryoblastic, Acute" by people in Profiles.
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Malinge S, Chlon T, Dor? LC, Ketterling RP, Tallman MS, Paietta E, Gamis AS, Taub JW, Chou ST, Weiss MJ, Crispino JD, Figueroa ME. Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes. Blood. 2013 Oct 03; 122(14):e33-43.
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Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Goldberg L, Birger Y, Izraeli S, Gamis AS, Smith FO, Woods WG, Taub J, Scherer CA, Bradner JE, Goh BC, Mercher T, Carpenter AE, Gould RJ, Clemons PA, Carr SA, Root DE, Schreiber SL, Stern AM, Crispino JD. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 2012 Aug 03; 150(3):575-89.
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Gamis AS, Alonzo TA, Gerbing RB, Hilden JM, Sorrell AD, Sharma M, Loew TW, Arceci RJ, Barnard D, Doyle J, Massey G, Perentesis J, Ravindranath Y, Taub J, Smith FO. Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971. Blood. 2011 Dec 22; 118(26):6752-9; quiz 6996.
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Bhat R, Malinge S, Gamis AS, Sorrell AD, Hilden JM, Ketterling RP, Paietta E, Tallman MS, Crispino JD. Mutational analysis of candidate tumor-associated genes in acute megakaryoblastic leukemia. Leukemia. 2009 Nov; 23(11):2159-60.
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Greene ME, Mundschau G, Wechsler J, McDevitt M, Gamis A, Karp J, Gurbuxani S, Arceci R, Crispino JD. Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome. Blood Cells Mol Dis. 2003 Nov-Dec; 31(3):351-6.
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Mundschau G, Gurbuxani S, Gamis AS, Greene ME, Arceci RJ, Crispino JD. Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis. Blood. 2003 Jun 01; 101(11):4298-300.
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