 Kevin F. Ginn, MD
| Title | Neuro-Oncologist and Director, Pediatric Brain Tumor Program |
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| Institution | Children's Mercy Kansas City |
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| Department | Pediatrics |
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| Address | 2401 Gillham Rd
Kansas City MO 64108
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| Title | Interim Director, Experimental Therapeutics Program |
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| Institution | Children's Mercy Kansas City |
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| Department | Pediatrics |
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| Title | Assistant Professor of Pediatrics |
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| Institution | University of Missouri-Kansas City |
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| Department | Pediatrics |
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| Title | Clinical Assistant Professor of Pediatrics |
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| Institution | University of Kansas Medical Center |
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| Department | Pediatrics |
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 Biography | Medical University of South Carolina College of Medicine, Charleston, SC | MD | 2005 | | | Louisiana State University Health Sciences Center, Children's Hospital, New Orleans, LA | Residency | 2008 | Pediatrics | | Children's Mercy Hospital, Kansas City, MO | Fellowship | 2011 | Pediatric Hematology/Oncology | | St. Jude Children's Research Hospital, Memphis, TN | Fellowship | 2012 | Pediatric Neuro-Oncology |
Overview Research Dr. Ginn's clinical focus is in the care of pediatric patients with central nervous system tumors. He directs the multi-disciplinary team at Children's Mercy providing care for approximately 50 brain and spine cord tumors a year. His current primary research role is as Interim Director of the Experimental Therapeutics in Pediatric Oncology Program. Dr. Ginn is a site Principal Investigator for approximately 30 early phase clinical trials. His team participates in Children's Oncology Group, Beat Childhood Cancer, Aflac Cancer Center and Industry Sponsored clinical trials. They also provide support to local Oncologist regarding expanded access to investigational agents and provide support for local investigator initiated trials. He is interested in expanding collaborations and bringing more local investigator trials through to completion.
Bibliography
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Eslin D, Zage PE, Bergendahl G, Lewis E, Roberts W, Kraveka J, Mitchell D, Isakoff MS, Rawwas J, Wada RK, Fluchel M, Brown VI, Ginn K, Higgins T, BeeravallyNagulapally A, Dykema K, Hanna G, Ferguson W, Saulnier Sholler GL. A phase II trial of nifurtimox combined with topotecan and cyclophosphamide for refractory or relapsed neuroblastoma and medulloblastoma. Int J Cancer. 2023 Sep 01; 153(5):1026-1034. PMID: 37246577.
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Cooley LD, Lansdon LA, Laurence K, Herriges JC, Zhang L, Repnikova EA, Joyce J, Thakor P, Warren L, Smith SC, Yoo B, Gener M, Ginn KF, Farooqi MS. Integrated genetic profiling of archival pediatric high-grade glial tumors and reassessment with 2021 WHO classification of paediatric CNS tumours. Cancer Genet. 2023 06; 274-275:10-20. PMID: 36917897.
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Messinger D, Harris MK, Cummings JR, Thomas C, Yang T, Sweha SR, Woo R, Siddaway R, Burkert M, Stallard S, Qin T, Mullan B, Siada R, Ravindran R, Niculcea M, Dowling AR, Bradin J, Ginn KF, Gener MAH, Dorris K, Vitanza NA, Schmidt SV, Spitzer J, Li J, Filbin MG, Cao X, Castro MG, Lowenstein PR, Mody R, Chinnaiyan A, Desprez PY, McAllister S, Dun MD, Hawkins C, Waszak SM, Venneti S, Koschmann C, Yadav VN. Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma. Neuro Oncol. 2023 01 05; 25(1):54-67. PMID: 35605606.
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Erker C, Mynarek M, Bailey S, Mazewski CM, Baroni L, Massimino M, Hukin J, Aguilera D, Cappellano AM, Ramaswamy V, Lassaletta A, Perreault S, Kline CN, Rajagopal R, Michaiel G, Zapotocky M, Santa-Maria Lopez V, La Madrid AM, Cacciotti C, Sandler ES, Hoffman LM, Klawinski D, Khan S, Salloum R, Hoppmann AL, Larouche V, Dorris K, Toledano H, Gilheeney SW, Abdelbaki MS, Wilson B, Tsang DS, Knipstein J, Oren MY, Shah S, Murray JC, Ginn KF, Wang ZJ, Fleischhack G, Obrecht D, Tonn S, Harrod VL, Matheson K, Crooks B, Strother DR, Cohen KJ, Hansford JR, Mueller S, Margol A, Gajjar A, Dhall G, Finlay JL, Northcott PA, Rutkowski S, Clifford SC, Robinson G, Bouffet E, Lafay-Cousin L. Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study. J Clin Oncol. 2023 04 01; 41(10):1921-1932. PMID: 36548930.
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Shah K, Boyd JW, Broussard JR, Ginn K, Rahmetulla R, Hurst K, Goyal RK. Adrenocortical Function in Children With Brain Tumors and Pediatric Hematopoietic Cell Transplantation Recipients. J Pediatr Hematol Oncol. 2022 Mar 01; 44(2):e469-e473. PMID: 34054040.
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Lucas CG, Gupta R, Wu J, Shah K, Ravindranathan A, Barreto J, Gener M, Ginn KF, Prall OWJ, Xu H, Kee D, Ko HS, Yaqoob N, Zia N, Florez A, Cha S, Perry A, Clarke JL, Chang SM, Berger MS, Solomon DA. EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma. Acta Neuropathol. 2022 01; 143(1):109-113. PMID: 34825267.
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Smith SC, Farooqi MS, Gener MA, Ginn K, Joyce JM, Bendorf TM, Cooley LD. Clinical Validation of Somatic Mutation Detection by the OncoScan CNV Plus Assay. J Mol Diagn. 2021 01; 23(1):29-37. PMID: 33080408.
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Prince EW, Whelan R, Mirsky DM, Stence N, Staulcup S, Klimo P, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Limbrick DD, Smith A, Drapeau A, Chern JJ, Kilburn L, Ginn K, Naftel R, Dudley R, Tyler-Kabara E, Jallo G, Handler MH, Jones K, Donson AM, Foreman NK, Hankinson TC. Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images. Sci Rep. 2020 10 09; 10(1):16885. PMID: 33037266.
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Prince E, Whelan R, Donson A, Staulcup S, Hengartner A, Vijmasi T, Agwu C, Lillehei KO, Foreman NK, Johnston JM, Massimi L, Anderson RCE, Souweidane MM, Naftel RP, Limbrick DD, Grant G, Niazi TN, Dudley R, Kilburn L, Jackson EM, Jallo GI, Ginn K, Smith A, Chern JJ, Lee A, Drapeau A, Krieger MD, Handler MH, Hankinson TC. Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets. Acta Neuropathol Commun. 2020 05 13; 8(1):68. PMID: 32404202.
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Porath B, Farooki S, Gener M, Amudhavalli SM, Grote L, Cooley LD, Ginn K, Farooqi MS. Occurrence and characterization of medulloblastoma in a patient with Curry-Jones syndrome. Clin Genet. 2020 04; 97(4):670-671. PMID: 31825089.
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Ginn KF, Fangman B, Terai K, Wise A, Ziazadeh D, Shah K, Gartrell R, Ricke B, Kimura K, Mathur S, Borrego-Diaz E, Farassati F. RalA is overactivated in medulloblastoma. J Neurooncol. 2016 10; 130(1):99-110. PMID: 27566179.
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Butler DF, Ginn KF, Daniel JF, Bloomer JR, Kats A, Shreve N, Myers GD. Bone marrow transplant for X-linked protoporphyria with severe hepatic fibrosis. Pediatr Transplant. 2015 Jun; 19(4):E106-10. PMID: 25856424.
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Zaky W, Dhall G, Khatua S, Brown RJ, Ginn KF, Gardner SL, Yildiz VO, Yankelevich M, Finlay JL. Choroid plexus carcinoma in children: the Head Start experience. Pediatr Blood Cancer. 2015 May; 62(5):784-9. PMID: 25662896.
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Radhi M, Fulbright JM, Ginn KF, Guest EM. Childhood cancer for the primary care physician. Prim Care. 2015 Mar; 42(1):43-55. PMID: 25634704.
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Ginn KF, Gajjar A. Atypical teratoid rhabdoid tumor: current therapy and future directions. Front Oncol. 2012; 2:114. PMID: 22988546.
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| Year | Publications |
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| 2012 | 1 | | 2014 | 1 | | 2015 | 2 | | 2016 | 1 | | 2019 | 1 | | 2020 | 3 | | 2021 | 1 | | 2022 | 2 | | 2023 | 3 |
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