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Mark A. Clements, MD, PhD

TitleMedical Director, Pediatric Clinical Research Unit
InstitutionChildren's Mercy Kansas City
DepartmentPediatrics
Address3101 Broadway
Kansas City MO 64111
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    Other Positions
    TitleDirector, Pediatric Endocrine/Diabetes Clinical Research
    InstitutionChildren's Mercy Kansas City
    DepartmentPediatrics

    TitleAssociate Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    Washington University School of Medicine, St. Louis, MO MD2003
    Washington University School of Medicine, St. Louis, MOPhD2003Neuroscience
    Children's Mercy Hospital, Kansas City, MOResidency2006Pediatrics
    Children's Mercy Hospital, Kansas City, MOFellowship2008Pediatric Endocrinology
    Collapse awards and honors
    2015Teacher of the year, Acellus
    2014Golden Apple mentor award, Children's Mercy
    2013Outstanding Teaching Section Award
    2012Top Doc, 435 Magazine
    2010Cure Award, American Diabetes Association Kansas City Chapter
    2008Physician Scientist Award, Children's Mercy Hospital

    Collapse Overview 

    Collapse Research 
    Collapse research overview
    Dr. Clements is recognized as an expert in diabetes data analytics with broad patient care and clinical research experience. He earned his Bachelor of Science degree in Biology and Chemistry (1993) at Butler University, Indianapolis, IN. Following, Dr. Clements earned his Medical Degree (2003) and PhD in Developmental Neuroscience (2003) at Washington University, St. Louis, MO. His previous training in the Medical Scientist Training Program at Washington University School of Medicine provided a strong foundation in basic science research. Dr. Clements trained as a clinical researcher at Children’s Mercy Hospital, where he has applied his skills to clinical trials of new diabetes treatments, clinical trials of treatments designed to prevent type 1 diabetes, intervention development research and risk prediction/health outcomes research in type 1 diabetes. He is Associate Professor at the University of Missouri-Kansas City. He served as Pediatric Chair of the T1D Exchange Clinic Registry from 2016-2019 and currently serves as data science co-lead for the T1D Exchange Quality Improvement Collaborative. He has a particular interest in the application of predictive analytics, real-time data listening, and digital health therapeutics to positively transform diabetes care.
    Collapse research activities and funding
    R01DK100779     (PATTON, SUSANA R)Aug 1, 2014 - Jul 31, 2019
    NIH
    Longitudinal test of adherence & control in kids new to T1 diabetes & 5-9 yrs old
    Role: Co-Investigator

    U01DK106984     (MOORE, WAYNE V.)Jul 20, 2015 - Apr 30, 2019
    NIH/NIDDK
    Type 1 Diabetes TrialNet Clinical Centers - Kansas City
    Role Description: Creation of a regional clinical trial sub-network for the TrialNet consortium. Will leverage a comprehensive business model for clinical trial management, real-time informatics, and quality improvement methodologies to increase the effectiveness and efficiency of recruitment and retention in TrialNet studies.
    Role: Principal Investigator

    DP3DK108211     (PATTON, SUSANA R)Dec 1, 2015 - May 30, 2020
    NIH
    An interactive mHealth app for better glycemic control in families of young kids with T1D
    Role Description: To build, refine, and pilot feasibility test a tailored diabetes education program for parents of young children. The tailored education program, called DIPPer Academy (Diabetes Information for Parents of Preschoolers) will use an online video-based and interactive micro-lecture format to deliver type 1 diabetes education and behavioral parent training to families of young children.
    Role: Co-Investigator

    G-2017PG-71D019     (CLEMENTS, MARK A)Feb 1, 2017 - Jan 31, 2020
    Helmsley Charitable Trust
    Improving type 1 diabetes care via predictive analytics and a learning health system
    Role Description: To develop and validate predictive models of at least two adverse diabetes health outcomes in youth using heterogeneous clinical and operational data. To trial preventive interventions in at-risk youth and their families and evaluate if the combination of predictive models and preventative interventions can improve health outcomes for youth with type 1 diabetes.
    Role: PI

    R01DK118514     (PATTON, SUSANA R)Apr 1, 2019 - Mar 31, 2024
    NIH
    Home Video-Based Telemedicine to Reduce Hypoglycemia Fear in Parents of Young Children
    Role Description: REDCHiP To build off of a prior R21-funded project by conducting a full randomized attention control trial a group-based telemedicine intervention (RED CHiP: Reducing Emotional Distress for Childhood Hypoglycemia in Parents), which was designed to reduce parental FH and improve glycemic levels and variability in young children with T1DM.
    Role: Co-Investigator

    3-SRA-2019-852-M-R     (MORAN, ANTOINETTE)Sep 1, 2019 - Aug 31, 2022
    JDRF
    CLVer-Hybrid Closed Loop Therapy for Beta Cell Preservation in New Onset Type 1 Diabetes: A Proof-of-Concept Study
    Role Description: the objective of this study is to test the efficacy of near-normal glycemic control with or withour verapamil on preservation of beta cell function in the recent diagnosis period for type 1 diabetes. Near-normal glycemic control is achieved via hybrid closed loop insulin delivery; verapamil has been shown to improve insulin secretion from beta cells. This study is a randomized controlled trial.
    Role: Co-Investigator: CMH site PI

    1-SRA-2020-893-Q-R     (HARRIS)Jan 1, 2020 - Dec 31, 2020
    JDRF
    Identification of the most vulnerable youth with T1D
    Role Description: To identify risk factors for recurrent hospitalization and high resource utilization among youth with T1D.
    Role: Co-Investigator

    2008-04043     (CLEMENTS, MARK A)Apr 1, 2020 - Mar 31, 2023
    Helmsley Charitable Trust
    Type 1 Diabetes Rapid Learning Lab
    Role Description: The objective of this project is to accelerate implementation of advanced predictive analytics (e.g., machine learning and deep learning) in clinical diabetes care. Near-term outcomes are predicted, with 1-2 new outcomes added cumulatively each calendar year. Current models predict 90-day rise in HbA1c and 180-day risk for hospital admission for diabetic ketoacidosis. Low-risk health care delivery interventions are deployed using quality improvement methods. Higher risk or novel interventions with unknown efficacy are deployed by embedding pilot clinical trials into Plan-Do-Study-Act cycles in the broader quality improvement projects. Up to 9 PDSA cycles with 4-9 novel interventions will be executed per year. Adoption packages will be created to guide other diabetes centers on implementing predictive analytics with novel interventions via quality improvement-based approaches.
    Role: PI

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Clements MA, Patton SR, McDonough RJ, Artman M. Are we there yet? Advanced technologies for young children with type 1 diabetes: comment in response to "Type 1 diabetes mellitus management in young children: implementation of current technologies". Pediatr Res. 2020 Jan 29. PMID: 31995810.
      View in: PubMed
    2. Rickels MR, Evans-Molina C, Bahnson HT, Ylescupidez A, Nadeau KJ, Hao W, Clements MA, Sherr JL, Pratley RE, Hannon TS, Shah VN, Miller KM, Greenbaum CJ. High residual C-peptide likely contributes to glycemic control in type 1 diabetes. J Clin Invest. 2020 Jan 02. PMID: 31895699.
      View in: PubMed
    3. Marker AM, Monzon AD, Nelson EL, Clements MA, Patton SR. An Intervention to Reduce Hypoglycemia Fear in Parents of Young Kids with Type 1 Diabetes Through Video-Based Telemedicine (REDCHiP): Trial Design, Feasibility, and Acceptability. Diabetes Technol Ther. 2020 Jan; 22(1):25-33. PMID: 31517512.
      View in: PubMed
    4. Patton SR, Clements MA, Marker AM, Nelson EL. Intervention to reduce hypoglycemia fear in parents of young kids using video-based telehealth (REDCHiP). Pediatr Diabetes. 2020 Feb; 21(1):112-119. PMID: 31610073.
      View in: PubMed
    5. Miller KM, Hermann J, Foster N, Hofer SE, Rickels MR, Danne T, Clements MA, Lilienthal E, Maahs DM, Holl RW. Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries. Diabetes Care. 2020 Jan; 43(1):e1-e2. PMID: 31672703.
      View in: PubMed
    6. Hermann JM, Miller KM, Hofer SE, Clements MA, Karges W, Foster NC, Fröhlich-Reiterer E, Rickels MR, Rosenbauer J, DeSalvo DJ, Holl RW, Maahs DM. The Transatlantic HbA1c gap: differences in glycaemic control across the lifespan between people included in the US T1D Exchange Registry and those included in the German/Austrian DPV registry. Diabet Med. 2019 Sep 26. PMID: 31557351.
      View in: PubMed
    7. Clements MA, Schwandt A, Donaghue KC, Miller K, Lück U, Couper JJ, Foster N, Schröder C, Phelan H, Maahs D, Prinz N, Craig ME. Five heterogeneous HbA1c trajectories from childhood to adulthood in youth with type 1 diabetes from three different continents: A group-based modeling approach. Pediatr Diabetes. 2019 11; 20(7):920-931. PMID: 31418521.
      View in: PubMed
    8. Marker AM, Patton SR, McDonough RJ, Feingold H, Simon L, Clements MA. Implementing clinic-wide depression screening for pediatric diabetes: An initiative to improve healthcare processes. Pediatr Diabetes. 2019 11; 20(7):964-973. PMID: 31264763.
      View in: PubMed
    9. Patton SR, Noser AE, Youngkin EM, Majidi S, Clements MA. Early Initiation of Diabetes Devices Relates to Improved Glycemic Control in Children with Recent-Onset Type 1 Diabetes Mellitus. Diabetes Technol Ther. 2019 07; 21(7):379-384. PMID: 31166808.
      View in: PubMed
    10. Tsai S, Patton S, DeLurgio S, Williams DD, Dileepan K, Karmazin A, Storm M, Clements M. A New Paediatric Diabetes Knowledge Test - M-WIKAD Development and Factor Analysis. Eur Endocrinol. 2019 Apr; 15(1):1-5. PMID: 31244902.
      View in: PubMed
    11. Marker AM, Monzon AD, Goggin KJ, Clements MA, Patton SR. Iterative development of a web-based intervention for families of young children with type 1 diabetes: DIPPer Academy. Clin Pract Pediatr Psychol. 2019 Mar; 7(1):20-30. PMID: 31662953.
      View in: PubMed
    12. Babar G, Clements M, Dai H, Raghuveer G. Assessment of biomarkers of inflammation and premature atherosclerosis in adolescents with type-1 diabetes mellitus. J Pediatr Endocrinol Metab. 2019 Feb 25; 32(2):109-113. PMID: 30710485.
      View in: PubMed
    13. Rancourt D, Foster N, Bollepalli S, Fitterman-Harris HF, Powers MA, Clements M, Smith LB. Test of the modified dual pathway model of eating disorders in individuals with type 1 diabetes. Int J Eat Disord. 2019 06; 52(6):630-642. PMID: 30802993.
      View in: PubMed
    14. Foster NC, Beck RW, Miller KM, Clements MA, Rickels MR, DiMeglio LA, Maahs DM, Tamborlane WV, Bergenstal R, Smith E, Olson BA, Garg SK. State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016-2018. Diabetes Technol Ther. 2019 02; 21(2):66-72. PMID: 30657336.
      View in: PubMed
    15. Noser AE, Dai H, Marker AM, Raymond JK, Majidi S, Clements MA, Stanek KR, Patton SR. Parental depression and diabetes-specific distress after the onset of type 1 diabetes in children. Health Psychol. 2019 Feb; 38(2):103-112. PMID: 30570283.
      View in: PubMed
    16. Reddy RK, Pooni R, Zaharieva DP, Senf B, El Youssef J, Dassau E, Doyle Iii FJ, Clements MA, Rickels MR, Patton SR, Castle JR, Riddell MC, Jacobs PG. Accuracy of Wrist-Worn Activity Monitors During Common Daily Physical Activities and Types of Structured Exercise: Evaluation Study. JMIR Mhealth Uhealth. 2018 Dec 10; 6(12):e10338. PMID: 30530451.
      View in: PubMed
    17. Aleppo G, Kanapka LG, Foster NC, Wu M, Clements MA, Rickels MR, McGill JB, Beck RW. CHEIROARTHROPATHY: A COMMON DISORDER IN PATIENTS IN THE T1D EXCHANGE. Endocr Pract. 2019 Feb; 25(2):138-143. PMID: 30383489.
      View in: PubMed
    18. Paprocki E, Staggs V, Patton S, Clements M. Insulin Pump Adherence Behaviors Do Not Correlate With Glycemic Variability Among Youth With Type 1 Diabetes (T1D). J Diabetes Sci Technol. 2019 01; 13(1):142-143. PMID: 30317860.
      View in: PubMed
    19. Lyons SK, Boyle CT, DeSalvo DJ, Rickels MR, Wood Heickman LK, Miller KM, Foster NC, Clements MA. Dyslipidaemia and statin use in individuals aged 10 to <40 years in the T1D Exchange clinic registry. Diabetes Obes Metab. 2019 01; 21(1):170-172. PMID: 30039636.
      View in: PubMed
    20. Noser AE, Majidi S, Finch J, Clements MA, Youngkin EM, Patton SR. Authoritarian parenting style predicts poorer glycemic control in children with new-onset type 1 diabetes. Pediatr Diabetes. 2018 11; 19(7):1315-1321. PMID: 30014608.
      View in: PubMed
    21. DeSalvo DJ, Miller KM, Hermann JM, Maahs DM, Hofer SE, Clements MA, Lilienthal E, Sherr JL, Tauschmann M, Holl RW. Continuous glucose monitoring and glycemic control among youth with type 1 diabetes: International comparison from the T1D Exchange and DPV Initiative. Pediatr Diabetes. 2018 11; 19(7):1271-1275. PMID: 29923262.
      View in: PubMed
    22. Redondo MJ, Libman I, Cheng P, Kollman C, Tosur M, Gal RL, Bacha F, Klingensmith GJ, Clements M. Response to Comment on Redondo et al. Racial/Ethnic Minority Youth With Recent-Onset Type 1 Diabetes Have Poor Prognostic Factors. Diabetes Care 2018;41:1017-1024. Diabetes Care. 2018 07; 41(7):e125-e126. PMID: 29934487.
      View in: PubMed
    23. Calkins-Smith AK, Marker AM, Clements MA, Patton SR. Hope and mealtime insulin boluses are associated with depressive symptoms and glycemic control in youth with type 1 diabetes mellitus. Pediatr Diabetes. 2018 11; 19(7):1309-1314. PMID: 29797445.
      View in: PubMed
    24. Marker AM, Noser AE, Knecht N, Clements MA, Patton SR. A Time-Friendly, Feasible Measure of Nutrition Knowledge in Type 1 Diabetes: The Electronic Nutrition and Carbohydrate Counting Quiz (eNCQ). J Diabetes Sci Technol. 2019 01; 13(1):68-74. PMID: 29857778.
      View in: PubMed
    25. Powers MA, Gal RL, Connor CG, Mangan M, Maahs DM, Clements MA, Mayer-Davis EJ. Eating patterns and food intake of persons with type 1 diabetes within the T1D exchange. Diabetes Res Clin Pract. 2018 Jul; 141:217-228. PMID: 29772288.
      View in: PubMed
    26. Charalampopoulos D, Hermann JM, Svensson J, Skrivarhaug T, Maahs DM, Akesson K, Warner JT, Holl RW, Birkebæk NH, Drivvoll AK, Miller KM, Svensson AM, Stephenson T, Hofer SE, Fredheim S, Kummernes SJ, Foster N, Hanberger L, Amin R, Rami-Merhar B, Johansen A, Dahl-Jørgensen K, Clements M, Hanas R. Exploring Variation in Glycemic Control Across and Within Eight High-Income Countries: A Cross-sectional Analysis of 64,666 Children and Adolescents With Type 1 Diabetes. Diabetes Care. 2018 06; 41(6):1180-1187. PMID: 29650804.
      View in: PubMed
    27. Redondo MJ, Libman I, Cheng P, Kollman C, Tosur M, Gal RL, Bacha F, Klingensmith GJ, Clements M. Racial/Ethnic Minority Youth With Recent-Onset Type 1 Diabetes Have Poor Prognostic Factors. Diabetes Care. 2018 05; 41(5):1017-1024. PMID: 29496742.
      View in: PubMed
    28. Marker AM, Noser AE, Clements MA, Patton SR. Shared Responsibility for Type 1 Diabetes Care Is Associated With Glycemic Variability and Risk of Glycemic Excursions in Youth. J Pediatr Psychol. 2018 01 01; 43(1):61-71. PMID: 28541572.
      View in: PubMed
    29. Offringa R, Sheng T, Parks L, Clements M, Kerr D, Greenfield MS. Digital Diabetes Management Application Improves Glycemic Outcomes in People With Type 1 and Type 2 Diabetes. J Diabetes Sci Technol. 2018 05; 12(3):701-708. PMID: 29277103.
      View in: PubMed
    30. Li X, Kover KL, Heruth DP, Watkins DJ, Guo Y, Moore WV, He LG, Zang M, Clements MA, Yan Y. Thioredoxin-interacting protein promotes high-glucose-induced macrovascular endothelial dysfunction. Biochem Biophys Res Commun. 2017 11 04; 493(1):291-297. PMID: 28890350.
      View in: PubMed
    31. Shoemaker A, Cheng P, Gal RL, Kollman C, Tamborlane WV, Klingensmith GJ, Clements MA, Hannon TS, Heptulla R, Less J, Wood J. Predictors of Loss to Follow-Up among Children with Type 2 Diabetes. Horm Res Paediatr. 2017; 87(6):377-384. PMID: 28505610.
      View in: PubMed
    32. Noser AE, Patton SR, Van Allen J, Nelson MB, Clements MA. Evaluating Parents' Self-Efficacy for Diabetes Management in Pediatric Type 1 Diabetes. J Pediatr Psychol. 2017 Apr 01; 42(3):296-303. PMID: 27550634.
      View in: PubMed
    33. Clements MA, Staggs VS. A Mobile App for Synchronizing Glucometer Data: Impact on Adherence and Glycemic Control Among Youths With Type 1 Diabetes in Routine Care. J Diabetes Sci Technol. 2017 05; 11(3):461-467. PMID: 28745097.
      View in: PubMed
    34. Patton SR, Noser AE, Clements MA, Dolan LM, Powers SW. Reexamining the Hypoglycemia Fear Survey for Parents of Young Children in a Sample of Children Using Insulin Pumps. Diabetes Technol Ther. 2017 02; 19(2):103-108. PMID: 28118046.
      View in: PubMed
    35. Hedén Ståhl C, Lind M, Svensson AM, Kosiborod M, Gudbjörnsdottir S, Pivodic A, Clements M, Rosengren A. Long-term excess risk of stroke in people with Type 2 diabetes in Sweden according to blood pressure level: a population-based case-control study. Diabet Med. 2017 04; 34(4):522-530. PMID: 27885698.
      View in: PubMed
    36. Noser AE, Huffhines L, Clements MA, Patton SR. Diabetes conflict outstrips the positive impact of self-efficacy on youth adherence and glycemic control in type 1 diabetes. Pediatr Diabetes. 2017 Nov; 18(7):614-618. PMID: 27859979.
      View in: PubMed
    37. Tsai SL, Clements MA, Apodaca TR. Reflections on Incorporating a Behavioral Intervention into a Busy Pediatric Subspecialty Clinic. J Pediatr Health Care. 2017 May - Jun; 31(3):404-408. PMID: 27692505.
      View in: PubMed
    38. Maliszewski G, Patton SR, Midyett LK, Clements MA. The Interactive Effect of Diabetes Family Conflict and Depression on Insulin Bolusing Behaviors for Youth. J Diabetes Sci Technol. 2017 05; 11(3):493-498. PMID: 27543271.
      View in: PubMed
    39. Patton SR, Driscoll KA, Clements MA. Adherence to Insulin Pump Behaviors in Young Children With Type 1 Diabetes Mellitus. J Diabetes Sci Technol. 2017 01; 11(1):87-91. PMID: 27390223.
      View in: PubMed
    40. Clements MA, DeLurgio SA, Williams DD, Habib S, Halpin K, Patton SR. Association of HbA1c to BOLUS Scores Among Youths with Type 1 Diabetes. Diabetes Technol Ther. 2016 06; 18(6):351-9. PMID: 27258122.
      View in: PubMed
    41. Patton SR, Clements MA. Psychological Reactions Associated With Continuous Glucose Monitoring in Youth. J Diabetes Sci Technol. 2016 05; 10(3):656-61. PMID: 26969141.
      View in: PubMed
    42. McDonough RJ, Clements MA, DeLurgio SA, Patton SR. Sleep duration and its impact on adherence in adolescents with type 1 diabetes mellitus. Pediatr Diabetes. 2017 06; 18(4):262-270. PMID: 27028035.
      View in: PubMed
    43. Van Allen J, Steele RG, Nelson MB, Peugh J, Egan A, Clements M, Patton SR. A Longitudinal Examination of Hope and Optimism and Their Role in Type 1 Diabetes in Youths. J Pediatr Psychol. 2016 Aug; 41(7):741-9. PMID: 26628250.
      View in: PubMed
    44. Corathers SD, Schoettker PJ, Clements MA, List BA, Mullen D, Ohmer A, Shah A, Lee J. Health-system-based interventions to improve care in pediatric and adolescent type 1 diabetes. Curr Diab Rep. 2015 Nov; 15(11):91. PMID: 26374568.
      View in: PubMed
    45. Patton SR, DeLurgio SA, Clements MA. Evaluation of the Average Daily Risk Range as a Measure of Glycemic Variability in Youths with Type 1 Diabetes. Diabetes Technol Ther. 2015 Nov; 17(11):795-800. PMID: 26535929.
      View in: PubMed
    46. Tancredi M, Rosengren A, Svensson AM, Kosiborod M, Pivodic A, Gudbjörnsdottir S, Wedel H, Clements M, Dahlqvist S, Lind M. Excess Mortality among Persons with Type 2 Diabetes. N Engl J Med. 2015 Oct 29; 373(18):1720-32. PMID: 26510021.
      View in: PubMed
    47. Rosengren A, Vestberg D, Svensson AM, Kosiborod M, Clements M, Rawshani A, Pivodic A, Gudbjörnsdottir S, Lind M. Long-term excess risk of heart failure in people with type 1 diabetes: a prospective case-control study. Lancet Diabetes Endocrinol. 2015 Nov; 3(11):876-85. PMID: 26388415.
      View in: PubMed
    48. Raman S, Dai H, DeLurgio SA, Williams DD, Lind M, Patton SR, Spertus JA, Kosiborod M, Clements MA. High hemoglobin A1c variability is associated with early risk of microalbuminuria in children with T1D. Pediatr Diabetes. 2016 09; 17(6):398-406. PMID: 26377593.
      View in: PubMed
    49. Patton SR, Clements MA, George K, Goggin K. "I Don't Want Them to Feel Different": A Mixed Methods Study of Parents' Beliefs and Dietary Management Strategies for Their Young Children with Type 1 Diabetes Mellitus. J Acad Nutr Diet. 2016 Feb; 116(2):272-82. PMID: 26260671.
      View in: PubMed
    50. Clements MA, Foster NC, Maahs DM, Schatz DA, Olson BA, Tsalikian E, Lee JM, Burt-Solorzano CM, Tamborlane WV, Chen V, Miller KM, Beck RW. Hemoglobin A1c (HbA1c) changes over time among adolescent and young adult participants in the T1D exchange clinic registry. Pediatr Diabetes. 2016 08; 17(5):327-36. PMID: 26153338.
      View in: PubMed
    51. Li X, Kover KL, Heruth DP, Watkins DJ, Moore WV, Jackson K, Zang M, Clements MA, Yan Y. New Insight Into Metformin Action: Regulation of ChREBP and FOXO1 Activities in Endothelial Cells. Mol Endocrinol. 2015 Aug; 29(8):1184-94. PMID: 26147751.
      View in: PubMed
    52. Patton SR, Goggin K, Clements MA. The Cost of a Healthier Diet for Young Children With Type 1 Diabetes Mellitus. J Nutr Educ Behav. 2015 Jul-Aug; 47(4):361-6.e1. PMID: 26164132.
      View in: PubMed
    53. Kover K, Yan Y, Tong PY, Watkins D, Li X, Tasch J, Hager M, Clements M, Moore WV. Osteocalcin protects pancreatic beta cell function and survival under high glucose conditions. Biochem Biophys Res Commun. 2015 Jun 19; 462(1):21-6. PMID: 25930995.
      View in: PubMed
    54. Willig LK, Petrikin JE, Smith LD, Saunders CJ, Thiffault I, Miller NA, Soden SE, Cakici JA, Herd SM, Twist G, Noll A, Creed M, Alba PM, Carpenter SL, Clements MA, Fischer RT, Hays JA, Kilbride H, McDonough RJ, Rosterman JL, Tsai SL, Zellmer L, Farrow EG, Kingsmore SF. Whole-genome sequencing for identification of Mendelian disorders in critically ill infants: a retrospective analysis of diagnostic and clinical findings. Lancet Respir Med. 2015 May; 3(5):377-87. PMID: 25937001.
      View in: PubMed
    55. Clements M, Matuleviciene V, Attvall S, Ekelund M, Pivodic A, Dahlqvist S, Fahlén M, Haraldsson B, Lind M. Predicting the effectiveness of insulin pump therapy on glycemic control in clinical practice: a retrospective study of patients with type 1 diabetes from 10 outpatient diabetes clinics in Sweden over 5 years. Diabetes Technol Ther. 2015 Jan; 17(1):21-8. PMID: 25470010.
      View in: PubMed
    56. Lind M, Svensson AM, Kosiborod M, Gudbjörnsdottir S, Pivodic A, Wedel H, Dahlqvist S, Clements M, Rosengren A. Glycemic control and excess mortality in type 1 diabetes. N Engl J Med. 2014 Nov 20; 371(21):1972-82. PMID: 25409370.
      View in: PubMed
    57. Clements MA, Lind M, Raman S, Patton SR, Lipska KJ, Fridlington AG, Tang F, Jones PG, Wu Y, Spertus JA, Kosiborod M. Age at diagnosis predicts deterioration in glycaemic control among children and adolescents with type 1 diabetes. BMJ Open Diabetes Res Care. 2014; 2(1):e000039. PMID: 25452876.
      View in: PubMed
    58. Patton SR, DeLurgio SA, Fridlington A, Cohoon C, Turpin AL, Clements MA. Frequency of mealtime insulin bolus predicts glycated hemoglobin in youths with type 1 diabetes. Diabetes Technol Ther. 2014 Aug; 16(8):519-23. PMID: 24773597.
      View in: PubMed
    59. Patton SR, Odar C, Midyett LK, Clements MA. Pilot study results for a novel behavior plus nutrition intervention for caregivers of young children with type 1 diabetes. J Nutr Educ Behav. 2014 Sep-Oct; 46(5):429-33. PMID: 24438850.
      View in: PubMed
    60. Patton SR, Clements MA. Average daily risk range as a measure for clinical research and routine care. J Diabetes Sci Technol. 2013 Sep 01; 7(5):1370-5. PMID: 24124966.
      View in: PubMed
    61. Yan Y, Li X, Kover K, Clements M, Ye P. CREB participates in the IGF-I-stimulation cyclin D1 transcription. Dev Neurobiol. 2013 Aug; 73(8):559-70. PMID: 23447091.
      View in: PubMed
    62. Carlsson BM, Attvall S, Clements M, Gumpeny SR, Pivodic A, Sternemalm L, Lind M. Insulin pump-long-term effects on glycemic control: an observational study at 10 diabetes clinics in Sweden. Diabetes Technol Ther. 2013 Apr; 15(4):302-7. PMID: 23537418.
      View in: PubMed
    63. Kover K, Tong PY, Watkins D, Clements M, Stehno-Bittel L, Novikova L, Bittel D, Kibiryeva N, Stuhlsatz J, Yan Y, Ye SQ, Moore WV. Expression and regulation of nampt in human islets. PLoS One. 2013; 8(3):e58767. PMID: 23536823.
      View in: PubMed
    64. Patton SR, Clements MA, Fridlington A, Cohoon C, Turpin AL, Delurgio SA. Frequency of mealtime insulin bolus as a proxy measure of adherence for children and youths with type 1 diabetes mellitus. Diabetes Technol Ther. 2013 Feb; 15(2):124-8. PMID: 23317372.
      View in: PubMed
    65. Patton SR, Clements MA. Continuous Glucose Monitoring Versus Self-monitoring of Blood Glucose in Children with Type 1 Diabetes- Are there Pros and Cons for Both? US Endocrinol. 2012; 8(1):27-29. PMID: 24312136.
      View in: PubMed
    66. Goldman J, Becker ML, Jones B, Clements M, Leeder JS. Development of biomarkers to optimize pediatric patient management: what makes children different? Biomark Med. 2011 Dec; 5(6):781-94. PMID: 22103612.
      View in: PubMed
    67. Kover K, Tong PY, Pacicca D, Clements M, Bodker AM, Eidson C, Sheldon M, Southard A, Zaidi A, Moore WV. Bone marrow cavity: a supportive environment for islet engraftment. Islets. 2011 May-Jun; 3(3):93-101. PMID: 21512317.
      View in: PubMed
    68. Karn RC, Clements MA. A comparison of the structures of the alpha:beta and alpha:gamma dimers of mouse salivary androgen-binding protein (ABP) and their differential steroid binding. Biochem Genet. 1999 Jun; 37(5-6):187-99. PMID: 10544804.
      View in: PubMed
    69. Sadovsky Y, Crawford PA, Woodson KG, Polish JA, Clements MA, Tourtellotte LM, Simburger K, Milbrandt J. Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):10939-43. PMID: 7479914.
      View in: PubMed
    Collapse presentations
    2019 Presentations

    Zhengzhou

    Xi'an

    Using Big Data and Predictive Analytics to Quality-Improve T1D Care, AACC, Anaheim, CA

    The T1D Exchange Quality Improvement Collaborative: What Have We Learned So Far? Achieving Targets In Diabetes Care, Barbara Davis Center for Childhood Diabetes, Keystone, Colorado,

    Innovation in Type 1 Diabetes Care, International Children’s Advisory Network Summit, Children’s Mercy Hospital, Kansas City, MO,

    Kids make excellent innovators! First Lego League as a model for youth-led innovation, International Children’s Advisory Network Summit, Children’s Mercy Hospital, Kansas City, MO,

    Improving T1D Care with Advanced Machine Learning and Natural Language Processing, Midwest Bioinformatics Conference University of Missouri-Kansas City

    What’s new in type 1 diabetes care; CMK ED Section Meeting Presentation,

    2018 Presentations

    TrialNet: What have we learned so far?, Grand Rounds, Stormont Vail Hospital, Topeka KS

    What’s new in diabetes technology, Xi’an Tangdu Hospital

    Hypoglycemia in children and infants, Henan Zhengzhou Children’s Hospital

    How to write a research manuscript, Henan Zhengzhou Children’s Hospital

    Adherence-promoting mobile applications in diabetes, Diabetes Technology meeting, Bethesda, MD

    T1D Exchange Clinic Registry and Network meeting, Tampa, FL

    Improving T1D Care with Advanced Machine Learning, ATTD, Vienna, Austria,

    Panel Member, Mobile Applications for promoting Adherence, Digital Diabetes Congress, San Francisco, CA,

    Data specification for the T1D Exchange Quality Care Collaborative, Pediatric Endocrine Society, Toronto, Canada,

    Data specification- T1D Exchange Quality Care Collaborative learning session, May, Cincinnati,

    Improving T1D Care- T1D Exchange Quality Care Collaborative learning session, May, Cincinnati,
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