Protein Phosphatase 2
"Protein Phosphatase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.
Descriptor ID |
D054648
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MeSH Number(s) |
D08.811.277.352.650.625.706 D12.644.360.583 D12.776.476.561
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Concept/Terms |
Protein Phosphatase 2, Catalytic Subunit, alpha Isoform- Protein Phosphatase 2, Catalytic Subunit, alpha Isoform
- Protein Phosphatase 2A, Catalytic Subunit, alpha Isoform
- Serine-Threonine-Protein Phosphatase 2A Catalytic Subunit alpha Isoform
- Serine Threonine Protein Phosphatase 2A Catalytic Subunit alpha Isoform
- PPP2CA Phosphatase
- Phosphatase, PPP2CA
Protein Phosphatase 2, Catalytic Subunit, beta Isoform- Protein Phosphatase 2, Catalytic Subunit, beta Isoform
- Protein Phosphatase 2A, Catalytic Subunit, beta Isoform
- Serine Threonine Protein Phosphatase 2A Catalytic Subunit beta Isoform
- PPP2CB Phosphatase
- Phosphatase, PPP2CB
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Below are MeSH descriptors whose meaning is more general than "Protein Phosphatase 2".
Below are MeSH descriptors whose meaning is more specific than "Protein Phosphatase 2".
This graph shows the total number of publications written about "Protein Phosphatase 2" by people in this website by year, and whether "Protein Phosphatase 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Phosphatase 2" by people in Profiles.
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Kurimchak A, Haines DS, Garriga J, Wu S, De Luca F, Sweredoski MJ, Deshaies RJ, Hess S, Gra?a X. Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55a holoenzyme. Mol Cell Biol. 2013 Aug; 33(16):3330-42.
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Menden H, Tate E, Hogg N, Sampath V. LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-? phosphorylation. Am J Physiol Lung Cell Mol Physiol. 2013 Mar 15; 304(6):L445-55.
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