Muscle Relaxants, Central
"Muscle Relaxants, Central" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
Descriptor ID |
D009125
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MeSH Number(s) |
D27.505.696.510 D27.505.696.663.700.600 D27.505.954.427.525
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Concept/Terms |
Muscle Relaxants, Central- Muscle Relaxants, Central
- Central Muscle Relaxants
- Relaxants, Central Muscle
- Centrally Acting Muscle Relaxants
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Below are MeSH descriptors whose meaning is more general than "Muscle Relaxants, Central".
Below are MeSH descriptors whose meaning is more specific than "Muscle Relaxants, Central".
This graph shows the total number of publications written about "Muscle Relaxants, Central" by people in this website by year, and whether "Muscle Relaxants, Central" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 | 2017 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Muscle Relaxants, Central" by people in Profiles.
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McLaughlin MJ, Fisher MT. A critical evaluation of oral baclofen in pediatric patients with cerebral palsy. J Pediatr Rehabil Med. 2023; 16(1):3-9.
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McLaughlin MJ, Ratnasingam D, McGhee E. Variability of Steady State Oral Baclofen Prescribing Practices in Pediatric Patients With Cerebral Palsy. Am J Phys Med Rehabil. 2020 05; 99(5):441-443.
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McLaughlin MJ, He Y, Brunstrom-Hernandez J, Thio LL, Carleton BC, Ross CJD, Gaedigk A, Lewandowski A, Dai H, Jusko WJ, Leeder JS. Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy. PM R. 2018 03; 10(3):235-243.
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He Y, Brunstrom-Hernandez JE, Thio LL, Lackey S, Gaebler-Spira D, Kuroda MM, Stashinko E, Hoon AH, Vargus-Adams J, Stevenson RD, Lowenhaupt S, McLaughlin JF, Christensen A, Dosa NP, Butler M, Schwabe A, Lopez C, Roge D, Kennedy D, Tilton A, Krach LE, Lewandowski A, Dai H, Gaedigk A, Leeder JS, Jusko WJ. Population pharmacokinetics of oral baclofen in pediatric patients with cerebral palsy. J Pediatr. 2014 May; 164(5):1181-1188.e8.
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