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Iwakuma, Tomoo

One or more keywords matched the following items that are connected to Iwakuma, Tomoo

Item Type	Name
Concept	Protein Binding
Concept	Protein Processing, Post-Translational
Concept	Protein Engineering
Concept	Tumor Suppressor Protein p53
Concept	Protein Structure, Tertiary
Concept	Protein Isoforms
Concept	cdc42 GTP-Binding Protein
Concept	rac1 GTP-Binding Protein
Concept	RNA-Binding Protein EWS
Concept	Ubiquitin-Protein Ligases
Concept	Protein Inhibitors of Activated STAT
Concept	Proto-Oncogene Protein c-fli-1
Concept	AMP-Activated Protein Kinases
Concept	Protein Multimerization
Concept	Unfolded Protein Response
Grant	The role of MDM2-MTBP axis in cancer metastasis
Academic Article	MTBP plays a crucial role in mitotic progression and chromosome segregation.
Academic Article	Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.
Academic Article	Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis.
Academic Article	Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.
Academic Article	IL-7Ra deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis.
Academic Article	MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4.
Academic Article	MDM2 binding protein, a novel metastasis suppressor.
Academic Article	A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.
Academic Article	Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing.
Academic Article	Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities.
Academic Article	DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway.
Academic Article	Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-?B and osteosarcoma progression.
Academic Article	Non-Canonical Cell Death Induced by p53.
Academic Article	p53 as a Regulator of Lipid Metabolism in Cancer.
Academic Article	Suppressive roles of A3AR and TMIGD3 i1 in osteosarcoma malignancy.
Academic Article	Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma.
Academic Article	Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase.
Academic Article	The interplay between mutant p53 and the mevalonate pathway.
Academic Article	Emerging Non-Canonical Functions and Regulation of p53.
Academic Article	EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells.
Academic Article	Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Academic Article	Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system.
Academic Article	Adriamycin inhibits human RH II/Gu RNA helicase activity by binding to its substrate.
Academic Article	TP53 in bone and soft tissue sarcomas.
Academic Article	The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice.
Academic Article	MDM2, an introduction.
Academic Article	Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
Academic Article	Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
Academic Article	Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.
Academic Article	Li-Fraumeni syndrome: a p53 family affair.
Academic Article	Crippling p53 activities via knock-in mutations in mouse models.
Academic Article	Mutant p53 suppresses innate immune signaling to promote tumorigenesis.
Academic Article	Mtbp haploinsufficiency in mice increases tumor metastasis.
Academic Article	The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss.
Academic Article	Mdm2 and Mdm4 loss regulates distinct p53 activities.
Academic Article	Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway.
Academic Article	A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.
Academic Article	A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.
Academic Article	DNAJA1 promotes cancer metastasis through interaction with mutant p53.
Academic Article	Regulation of p53 and Cancer Signaling by Heat Shock Protein 40/J-Domain Protein Family Members.
Academic Article	Therapeutic potential of combating cancer by restoring wild-type p53 through mRNA nanodelivery.

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