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Search Results to J. Steven Leeder

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One or more keywords matched the following items that are connected to Leeder, J. Steven

Item TypeName
Concept Dextromethorphan
Academic Article Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.
Academic Article Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine.
Academic Article Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans.
Academic Article Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".
Academic Article Comparison of various urine collection intervals for caffeine and dextromethorphan phenotyping in children.
Academic Article Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.
Academic Article Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail.
Academic Article CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.
Academic Article Effect of diet on the development of drug metabolism by cytochrome P-450 enzymes in healthy infants.
Academic Article Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.
Academic Article Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype.
Academic Article The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
Academic Article Evaluation of a [13C]-dextromethorphan breath test to assess CYP2D6 phenotype.
Academic Article Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics.
Academic Article Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping.
Academic Article Quantification of intraindividual variability and the influence of menstrual cycle phase on CYP2D6 activity as measured by dextromethorphan phenotyping.
Academic Article Investigation of terbinafine as a CYP2D6 inhibitor in vivo.
Academic Article Potent inhibition of cytochrome P-450 2D6-mediated dextromethorphan O-demethylation by terbinafine.
Academic Article Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.
Academic Article Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.
Academic Article Limitations of dextromethorphan N-demethylation as a measure of CYP3A activity.
Academic Article Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".

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  • Dextromethorphan