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Leeder, J. Steven

One or more keywords matched the following items that are connected to Leeder, J. Steven

Item Type	Name
Concept	Dextromethorphan
Academic Article	Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.
Academic Article	Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine.
Academic Article	Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans.
Academic Article	Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".
Academic Article	Comparison of various urine collection intervals for caffeine and dextromethorphan phenotyping in children.
Academic Article	Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.
Academic Article	Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail.
Academic Article	CYP2D636 gene arrangements within the cyp2d6 locus: association of CYP2D636 with poor metabolizer status.
Academic Article	Effect of diet on the development of drug metabolism by cytochrome P-450 enzymes in healthy infants.
Academic Article	Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.
Academic Article	Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype.
Academic Article	The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
Academic Article	Evaluation of a [13C]-dextromethorphan breath test to assess CYP2D6 phenotype.
Academic Article	Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics.
Academic Article	Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping.
Academic Article	Quantification of intraindividual variability and the influence of menstrual cycle phase on CYP2D6 activity as measured by dextromethorphan phenotyping.
Academic Article	Investigation of terbinafine as a CYP2D6 inhibitor in vivo.
Academic Article	Potent inhibition of cytochrome P-450 2D6-mediated dextromethorphan O-demethylation by terbinafine.
Academic Article	Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.
Academic Article	Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.
Academic Article	Limitations of dextromethorphan N-demethylation as a measure of CYP3A activity.
Academic Article	Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".
Academic Article	The Impact of the CYP2D6 "Enhancer" Single Nucleotide Polymorphism on CYP2D6 Activity.
Academic Article	A longitudinal study of cytochrome P450 2D6 (CYP2D6) activity during adolescence.

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Dextromethorphan