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NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells.
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has minor subject area list
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Adolescent; Antineoplastic Agents, Hormonal; Base Sequence; Child; Child, Preschool; DNA Methylation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Leukemic; HEK293 Cells; Humans; Infant; Infant, Newborn; Inflammasomes; Neoplasm Recurrence, Local; NLR Family, Pyrin Domain-Containing 3 Protein; Prednisolone; Proteolysis; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation
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