A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.

Descriptor ID	D006223
MeSH Number(s)	C04.445.435 C04.651.435 C04.700.435 C16.320.700.435
Concept/Terms	Hamartoma Syndrome, Multiple Hamartoma Syndrome, Multiple Hamartoma Syndromes, Multiple Multiple Hamartoma Syndromes Multiple Hamartoma Syndrome Cowden's Disease Cowdens Disease Cowden's Syndrome Cowdens Syndrome Cowden Disease Cowden Syndrome Lhermitte-Duclos Disease Lhermitte-Duclos Disease Lhermitte Duclos Disease Dysplastic Gangliocytoma of Cerebellum Cerebellum Dysplastic Gangliocytoma Cerebellum Dysplastic Gangliocytomas Dysplastic Gangliocytoma of the Cerebellum PTEN Hamartoma Tumor Syndrome PTEN Hamartoma Tumor Syndrome Bannayan-Riley-Ruvalcaba Syndrome Bannayan-Riley-Ruvalcaba Syndrome Bannayan Riley Ruvalcaba Syndrome Macrocephaly, Multiple Lipomas, and Hemangiomata Macrocephaly, Pseudopapilledema, and Multiple Hemangiomas Ruvalcaba-Myhre Syndrome Myhre-Riley-Smith Syndrome Myhre Riley Smith Syndrome Riley-Smith Syndrome Riley Smith Syndrome Ruvalcaba-Myhre-Smith Syndrome Ruvalcaba Myhre Smith Syndrome Bannayan-Ruvalcaba-Riley Syndrome Bannayan-Zonana Syndrome Bannayan Zonana Syndrome Macrocephaly, Pseudopapilledema, and Multiple Hemangiomata

Below are MeSH descriptors whose meaning is more general than "Hamartoma Syndrome, Multiple".

Below are MeSH descriptors whose meaning is related to "Hamartoma Syndrome, Multiple".

Below are MeSH descriptors whose meaning is more specific than "Hamartoma Syndrome, Multiple".