Disulfiram
"Disulfiram" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
| Descriptor ID |
D004221
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| MeSH Number(s) |
D02.241.081.251.869.220.250 D02.886.520.150.175 D02.886.706.200.200
|
| Concept/Terms |
Disulfiram- Disulfiram
- Tetraethylthiuram Disulfide
- Disulfide, Tetraethylthiuram
- Bis(diethylthiocarbamoyl) Disulfide
- Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
Antabus- Antabus
- Bohm Brand of Disulfiram
- Dumex Brand of Disulfiram
- Altana Pharma Brand of Disulfiram
Esperal- Esperal
- Sanofi Synthelabo Brand of Disulfiram
Antabuse- Antabuse
- Odyssey Brand of Disulfiram
- Orphan Brand of Disulfiram
- Allphar Brand of Disulfiram
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Below are MeSH descriptors whose meaning is more general than "Disulfiram".
Below are MeSH descriptors whose meaning is more specific than "Disulfiram".
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Below are the most recent publications written about "Disulfiram" by people in Profiles.
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Heemskerk AA, van Haandel L, Woods JM, McCance-Katz EF, Williams TD, Stobaugh JF, Faiman MD. LC-MS/MS method for the determination of carbamathione in human plasma. J Pharm Biomed Anal. 2011 Mar 25; 54(4):799-806.