 Diphosphonates
"Diphosphonates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
| Descriptor ID |
D004164
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| MeSH Number(s) |
D02.705.429.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Diphosphonates".
Below are MeSH descriptors whose meaning is more specific than "Diphosphonates".
This graph shows the total number of publications written about "Diphosphonates" by people in this website by year, and whether "Diphosphonates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 3 | 0 | 3 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Diphosphonates" by people in Profiles.
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Liu W, Lee B, Nagamani SCS, Nicol L, Rauch F, Rush ET, Sutton VR, Orwoll E. Approach to the Patient: Pharmacological Therapies for Fracture Risk Reduction in Adults With Osteogenesis Imperfecta. J Clin Endocrinol Metab. 2023 06 16; 108(7):1787-1796.
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Azzam KA, Rush ET, Burke BR, Nabower AM, Esposito PW. Mid-term Results of Femoral and Tibial Osteotomies and Fassier-Duval Nailing in Children With Osteogenesis Imperfecta. J Pediatr Orthop. 2018 Jul; 38(6):331-336.
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Kreikemeier RM, Gosnell H, Halbur LM, Rush ET. A retrospective review of initial bisphosphonate infusion in an inpatient vs. outpatient setting for bisphosphonate na?ve patients. J Pediatr Endocrinol Metab. 2017 Oct 26; 30(10):1105-1110.
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Sebestyen JF, Srivastava T, Alon US. Bisphosphonates use in children. Clin Pediatr (Phila). 2012 Nov; 51(11):1011-24.
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Winston MJ, Srivastava T, Jarka D, Alon US. Bisphosphonates for pain management in children with benign cartilage tumors. Clin J Pain. 2012 Mar-Apr; 28(3):268-72.
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Rush ET, DeHaai K, Kreikemeier RM, Lutz RE. Evaluation and comparison of safety, convenience and cost of administering intravenous pamidronate infusions to children in the home and ambulatory care settings. J Pediatr Endocrinol Metab. 2012; 25(5-6):493-7.
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Srivastava T, Dai H, Haney CJ, Alon US. Serum 25-hydroxyvitamin D level and acute-phase reaction following initial intravenous bisphosphonate. J Bone Miner Res. 2011 Feb; 26(2):437-8.
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Srivastava T, Haney CJ, Alon US. Atorvastatin may have no effect on acute phase reaction in children after intravenous bisphosphonate infusion. J Bone Miner Res. 2009 Feb; 24(2):334-7.
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Auron A, Tal L, Srivastava T, Alon US. Reversal of hypercalcemic acute kidney injury by treatment with intravenous bisphosphonates. Pediatr Nephrol. 2009 Mar; 24(3):613-7.
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Waterhouse KM, Auron A, Srivastava T, Haney C, Alon US. Sustained beneficial effect of intravenous bisphosphonates after their discontinuation in children. Pediatr Nephrol. 2007 Feb; 22(2):282-7.
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