Clofibrate
"Clofibrate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
| Descriptor ID |
D002994
|
| MeSH Number(s) |
D02.241.081.114.968.500.500.195 D02.355.726.305.500.195 D02.455.426.559.389.657.654.305.500.195
|
| Concept/Terms |
Clofibrate- Clofibrate
- Ethyl Chlorophenoxyisobutyrate
- Chlorophenoxyisobutyrate, Ethyl
- Clofibric Acid, Ethyl Ester
|
Below are MeSH descriptors whose meaning is more general than "Clofibrate".
Below are MeSH descriptors whose meaning is more specific than "Clofibrate".
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Below are the most recent publications written about "Clofibrate" by people in Profiles.
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Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD. Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARa-Dependent Manner. Toxicol Sci. 2017 Dec 01; 160(2):351-360.
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Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD. Activation of PPARa decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion. Toxicol Appl Pharmacol. 2018 01 01; 338:112-123.