Cell Transformation, Neoplastic
"Cell Transformation, Neoplastic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Descriptor ID |
D002471
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MeSH Number(s) |
C04.697.098.500 C23.550.727.098.500
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Concept/Terms |
Cell Transformation, Neoplastic- Cell Transformation, Neoplastic
- Tumorigenic Transformation
- Transformation, Tumorigenic
- Transformations, Tumorigenic
- Tumorigenic Transformations
- Transformation, Neoplastic Cell
- Neoplastic Cell Transformation
- Cell Transformations, Neoplastic
- Neoplastic Cell Transformations
- Transformations, Neoplastic Cell
- Neoplastic Transformation, Cell
- Cell Neoplastic Transformation
- Cell Neoplastic Transformations
- Neoplastic Transformations, Cell
- Transformation, Cell Neoplastic
- Transformations, Cell Neoplastic
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Below are MeSH descriptors whose meaning is more general than "Cell Transformation, Neoplastic".
Below are MeSH descriptors whose meaning is more specific than "Cell Transformation, Neoplastic".
This graph shows the total number of publications written about "Cell Transformation, Neoplastic" by people in this website by year, and whether "Cell Transformation, Neoplastic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 2003 | 1 | 0 | 1 | 2004 | 1 | 0 | 1 | 2005 | 1 | 0 | 1 | 2008 | 1 | 1 | 2 | 2010 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 | 2015 | 2 | 0 | 2 | 2016 | 0 | 1 | 1 | 2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Transformation, Neoplastic" by people in Profiles.
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Ghosh M, Saha S, Bettke J, Nagar R, Parrales A, Iwakuma T, van der Velden AWM, Martinez LA. Mutant p53 suppresses innate immune signaling to promote tumorigenesis. Cancer Cell. 2021 04 12; 39(4):494-508.e5.
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Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, Gong S, Gao P, Iwakuma T, Molina-Vila MA, Chen BP, Zhang Y, Ji T, Mo Q, Chen P, Hu J, Wang S, Zhou J, Lu H, Gao Q. Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. EBioMedicine. 2019 Feb; 40:92-105.
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Orlando G, Law PJ, Cornish AJ, Dobbins SE, Chubb D, Broderick P, Litchfield K, Hariri F, Pastinen T, Osborne CS, Taipale J, Houlston RS. Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer. Nat Genet. 2018 10; 50(10):1375-1380.
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Parrales A, Ranjan A, Iyer SV, Padhye S, Weir SJ, Roy A, Iwakuma T. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016 Nov; 18(11):1233-1243.
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Sasaki H, Iyer SV, Sasaki K, Tawfik OW, Iwakuma T. An improved intrafemoral injection with minimized leakage as an orthotopic mouse model of osteosarcoma. Anal Biochem. 2015 Oct 01; 486:70-4.
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Koptyra M, Park TJ, Curran T. Crk and CrkL are required for cell transformation by v-fos and v-ras. Mol Carcinog. 2016 Jan; 55(1):97-104.
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Malinge S, Chlon T, Dor? LC, Ketterling RP, Tallman MS, Paietta E, Gamis AS, Taub JW, Chou ST, Weiss MJ, Crispino JD, Figueroa ME. Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes. Blood. 2013 Oct 03; 122(14):e33-43.
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Post SM, Quint?s-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G. A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development. Cancer Cell. 2010 Sep 14; 18(3):220-30.
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Fraser JD, Briggs SE, St Peter SD, De Petris G, Heppell J. Intussusception in the adult: an unsuspected case of Peutz-Jeghers syndrome with review of the literature. Fam Cancer. 2009; 8(2):95-101.
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Perry JM, Li L. Self-renewal versus transformation: Fbxw7 deletion leads to stem cell activation and leukemogenesis. Genes Dev. 2008 May 01; 22(9):1107-9.
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