 Arginase
"Arginase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ureahydrolase that catalyzes the hydrolysis of arginine or canavanine to yield L-ornithine (ORNITHINE) and urea. Deficiency of this enzyme causes HYPERARGININEMIA. EC 3.5.3.1.
| Descriptor ID |
D001119
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| MeSH Number(s) |
D08.811.277.913.292
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| Concept/Terms |
Arginase- Arginase
- Liver Immunoregulatory Protein
- Immunoregulatory Protein, Liver
- Protein, Liver Immunoregulatory
- Liver-Derived Inhibitory Protein
- Inhibitory Protein, Liver-Derived
- Liver Derived Inhibitory Protein
- Protein, Liver-Derived Inhibitory
- Hepatic Proliferation Inhibitor
- Inhibitor, Hepatic Proliferation
- Proliferation Inhibitor, Hepatic
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Below are MeSH descriptors whose meaning is more general than "Arginase".
Below are MeSH descriptors whose meaning is more specific than "Arginase".
This graph shows the total number of publications written about "Arginase" by people in this website by year, and whether "Arginase" was a major or minor topic of these publications.
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Below are the most recent publications written about "Arginase" by people in Profiles.
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Iyamu EW, Perdew HA, Woods GM. Oxidant-mediated modification of the cellular thiols is sufficient for arginase activation in cultured cells. Mol Cell Biochem. 2012 Jan; 360(1-2):159-68.
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Iyamu E, Perdew H, Woods G. Growth inhibitory and differentiation effects of chloroquine and its analogue on human leukemic cells potentiate fetal hemoglobin production by targeting the polyamine pathway. Biochem Pharmacol. 2009 Mar 15; 77(6):1021-8.
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Iyamu EW, Perdew H, Woods GM. Cysteine-iron promotes arginase activity by driving the Fenton reaction. Biochem Biophys Res Commun. 2008 Nov 07; 376(1):116-20.
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Iyamu EW, Asakura T, Woods GM. A colorimetric microplate assay method for high-throughput analysis of arginase activity in vitro. Anal Biochem. 2008 Dec 15; 383(2):332-4.
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Iyamu EW, Jamal S, Ekekezie C, Woods GM. In vitro evidence of the inhibitory capacity of chloroquine on arginase activity in sickle erythrocytes. Br J Haematol. 2007 10; 139(2):337-43.
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Iyamu EW, Cecil R, Parkin L, Woods G, Ohene-Frempong K, Asakura T. Modulation of erythrocyte arginase activity in sickle cell disease patients during hydroxyurea therapy. Br J Haematol. 2005 Nov; 131(3):389-94.
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