Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Descriptor ID |
D000544
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MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
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Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Disease, Alzheimer
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Syndrome, Alzheimer
- Alzheimer Dementia (AD)
- Dementia, Alzheimer (AD)
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Primary Senile Degenerative Dementia
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Senile Dementia, Alzheimer Type
- Alzheimer Type Senile Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer's Disease
- Disease, Alzheimer's
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Vidoni ED, Yeh HW, Morris JK, Newell KL, Alqahtani A, Burns NC, Burns JM, Billinger SA. Cerebral ?-Amyloid Angiopathy Is Associated with Earlier Dementia Onset in Alzheimer's Disease. Neurodegener Dis. 2016; 16(3-4):218-24.
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Han B, Chen XW, Talebizadeh Z, Xu H. Genetic studies of complex human diseases: characterizing SNP-disease associations using Bayesian networks. BMC Syst Biol. 2012; 6 Suppl 3:S14.
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Hitt B, Riordan SM, Kukreja L, Eimer WA, Rajapaksha TW, Vassar R. ?-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects. J Biol Chem. 2012 Nov 09; 287(46):38408-25.
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Youmans KL, Tai LM, Kanekiyo T, Stine WB, Michon SC, Nwabuisi-Heath E, Manelli AM, Fu Y, Riordan S, Eimer WA, Binder L, Bu G, Yu C, Hartley DM, LaDu MJ. Intraneuronal A? detection in 5xFAD mice by a new A?-specific antibody. Mol Neurodegener. 2012 Mar 16; 7:8.
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Ross MG, Desai M, Khorram O, McKnight RA, Lane RH, Torday J. Gestational programming of offspring obesity: a potential contributor to Alzheimer's disease. Curr Alzheimer Res. 2007 Apr; 4(2):213-7.
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Zdanys KF, Kleiman TG, MacAvoy MG, Black BT, Rightmer TE, Grey M, Garman KS, Tampi RR, Gelernter J, van Dyck CH. Apolipoprotein E epsilon4 allele increases risk for psychotic symptoms in Alzheimer's disease. Neuropsychopharmacology. 2007 Jan; 32(1):171-9.
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Homayouni R, Rice DS, Sheldon M, Curran T. Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. J Neurosci. 1999 Sep 01; 19(17):7507-15.
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