 Filamins
"Filamins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.
| Descriptor ID |
D064448
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| MeSH Number(s) |
A11.284.430.214.190.750.050.414 D05.750.078.730.315 D12.776.210.249 D12.776.220.525.315
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| Concept/Terms |
Filamin B- Filamin B
- B, Filamin
- Filamin 1-Like Protein
- 1-Like Protein, Filamin
- 1-Like Proteins, Filamin
- Filamin 1 Like Protein
- Filamin 1-Like Proteins
- Protein, Filamin 1-Like
- Proteins, Filamin 1-Like
- beta-Filamin
- beta Filamin
- beta-Filamins
Filamin A- Filamin A
- A, Filamin
- alpha-Filamin
- alpha Filamin
- alpha-Filamins
- Filamin 1
- 1, Filamin
- 280 kDa Actin-Binding Protein
- 280 kDa Actin Binding Protein
Filamin C- Filamin C
- C, Filamin
- Cs, Filamin
- Filamin Cs
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Below are MeSH descriptors whose meaning is more general than "Filamins".
Below are MeSH descriptors whose meaning is more specific than "Filamins".
This graph shows the total number of publications written about "Filamins" by people in this website by year, and whether "Filamins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Filamins" by people in Profiles.
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Wilson SG, Jones MR, Mullin BH, Dick IM, Richards JB, Pastinen TM, Grundberg E, Ljunggren O, Surdulescu GL, Dudbridge F, Elliott KS, Cervino AC, Spector TD, Prince RL. Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro. J Bone Miner Res. 2009 Dec; 24(12):1989-97.
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