Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.
Descriptor ID |
D064197
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MeSH Number(s) |
D08.811.464.938.750.092.625 D12.776.167.024.625
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Concept/Terms |
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