An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.

Descriptor ID	D000224
MeSH Number(s)	C19.053.500.263 C20.111.163
Concept/Terms	Addison Disease Addison Disease Disease, Addison Primary Adrenal Insufficiency Adrenal Insufficiency, Primary Primary Hypoadrenalism Hypoadrenalism, Primary Hypoadrenalisms, Primary Addison's Disease Addisons Disease Primary Adrenocortical Insufficiency Adrenocortical Insufficiencies, Primary Adrenocortical Insufficiency, Primary Insufficiencies, Primary Adrenocortical Insufficiency, Primary Adrenocortical Primary Adrenocortical Insufficiencies

Below are MeSH descriptors whose meaning is more general than "Addison Disease".

Below are MeSH descriptors whose meaning is related to "Addison Disease".

Below are MeSH descriptors whose meaning is more specific than "Addison Disease".