A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.

Descriptor ID	D053484
MeSH Number(s)	D08.811.277.040.025.159.249 D08.811.399.340.249
Concept/Terms	RecQ Helicases RecQ Helicases Helicases, RecQ RecQ Protein RecQ Family of DNA Helicases RecQL Helicase RecQL Helicase Helicase, RecQL RECQL1 Helicase Helicase, RECQL1 DNA Helicase RecQL DNA-Dependent ATPase Q1 DNA Dependent ATPase Q1 ATP-Dependent DNA Helicase Q1 ATP Dependent DNA Helicase Q1 DNA Helicase Q1 RecQ4 Helicase RecQ4 Helicase RTS Helicase Helicase, RTS RecQL4 Helicase Helicase, RecQL4 ATP-Dependent DNA Helicase Q4 ATP Dependent DNA Helicase Q4 DNA Helicase RecQL4 RecQ5 Helicase RecQ5 Helicase Helicase, RecQ5 RecQ5L Helicase Helicase, RecQ5L ATP-Dependent DNA Helicase Q5 ATP Dependent DNA Helicase Q5 RecQ2 Helicase RecQ2 Helicase Helicase, RecQ2 RecQL3 Helicase Helicase, RecQL3 DNA Helicase, RecQ-like type 2 DNA Helicase, RecQ like type 2 RecQ3 Helicase RecQ3 Helicase Helicase, RecQ3 RecQL2 Helicase Helicase, RecQL2

Below are MeSH descriptors whose meaning is more general than "RecQ Helicases".

Below are MeSH descriptors whose meaning is related to "RecQ Helicases".

Below are MeSH descriptors whose meaning is more specific than "RecQ Helicases".