Edar-Associated Death Domain Protein
"Edar-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.
| Descriptor ID |
D053362
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| MeSH Number(s) |
D12.644.360.024.296.100 D12.644.360.024.500.061 D12.644.360.075.421.100 D12.776.157.057.024.100 D12.776.157.057.500.061 D12.776.476.024.375.100 D12.776.476.024.500.061 D12.776.476.075.421.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Edar-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "Edar-Associated Death Domain Protein".
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