Transcription Factor RelA
"Transcription Factor RelA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subunit of NF-kappa B that is primarily responsible for its transactivation function. It contains a C-terminal transactivation domain and an N-terminal domain with homology to PROTO-ONCOGENE PROTEINS C-REL.
Descriptor ID |
D051996
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MeSH Number(s) |
D12.776.260.600.249 D12.776.660.600.249 D12.776.930.600.249
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Concept/Terms |
Transcription Factor RelA- Transcription Factor RelA
- RelA, Transcription Factor
- NF-kappa B p65
- NF kappa B p65
- p65, NF-kappa B
- NF-kappa B p65 Subunit
- NF kappa B p65 Subunit
- Transcription Factor p65
- p65, Transcription Factor
- p65 Transcription Factor
- Transcription Factor, p65
- v-Rel Reticuloendotheliosis Viral Oncogene Homolog A
- v Rel Reticuloendotheliosis Viral Oncogene Homolog A
- NF-kappaB 65-kDa
- NF kappaB 65 kDa
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor RelA".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor RelA".
This graph shows the total number of publications written about "Transcription Factor RelA" by people in this website by year, and whether "Transcription Factor RelA" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor RelA" by people in Profiles.
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van Dijk AD, Hoff FW, Qiu Y, Gerbing RB, Gamis AS, Aplenc R, Kolb EA, Alonzo TA, Meshinchi S, Jenkins GN, de Bont ESJM, Kornblau SM, Horton TM. Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-?B subunit RelA. Proteomics Clin Appl. 2022 03; 16(2):e2100072.
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Wu S, Yang W, De Luca F. Insulin-Like Growth Factor-Independent Effects of Growth Hormone on Growth Plate Chondrogenesis and Longitudinal Bone Growth. Endocrinology. 2015 Jul; 156(7):2541-51.
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Rentea RM, Welak SR, Fredrich K, Donohoe D, Pritchard KA, Oldham KT, Gourlay DM, Liedel JL. Early enteral stressors in newborns increase inflammatory cytokine expression in a neonatal necrotizing enterocolitis rat model. Eur J Pediatr Surg. 2013 Feb; 23(1):39-47.
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Wu S, Morrison A, Sun H, De Luca F. Nuclear factor-kappaB (NF-kappaB) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2. J Biol Chem. 2011 Jul 15; 286(28):24726-34.
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Wu S, Fadoju D, Rezvani G, De Luca F. Stimulatory effects of insulin-like growth factor-I on growth plate chondrogenesis are mediated by nuclear factor-kappaB p65. J Biol Chem. 2008 Dec 05; 283(49):34037-44.
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Wu S, Flint JK, Rezvani G, De Luca F. Nuclear factor-kappaB p65 facilitates longitudinal bone growth by inducing growth plate chondrocyte proliferation and differentiation and by preventing apoptosis. J Biol Chem. 2007 Nov 16; 282(46):33698-33706.
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