 Receptors, Scavenger
"Receptors, Scavenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of structurally diverse cell surface receptors that mediate endocytic uptake of modified LIPOPROTEINS. Scavenger receptors are expressed by MYELOID CELLS and some ENDOTHELIAL CELLS, and were originally characterized based on their ability to bind acetylated LOW-DENSITY LIPOPROTEINS. They can also bind a variety of other polyanionic ligand. Certain scavenger receptors can internalize micro-organisms as well as apoptotic cells.
| Descriptor ID |
D051116
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| MeSH Number(s) |
D12.776.543.750.705.940 D12.776.543.750.710.450.750
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| Concept/Terms |
Receptors, Scavenger- Receptors, Scavenger
- Acetyl-LDL Receptors
- Acetyl LDL Receptors
- Receptors, Acetyl-LDL
- Scavenger Receptors
- Receptor, Acetyl-LDL
- Receptor, Acetyl LDL
- Scavenger Receptor
- Receptor, Scavenger
- Acetyl-LDL Receptor
- Acetyl LDL Receptor
- Acetylated LDL Receptor
- LDL Receptor, Acetylated
- Receptor, Acetylated LDL
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Below are MeSH descriptors whose meaning is more general than "Receptors, Scavenger".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Scavenger".
This graph shows the total number of publications written about "Receptors, Scavenger" by people in this website by year, and whether "Receptors, Scavenger" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 3 | 3 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptors, Scavenger" by people in Profiles.
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de La Llera-Moya M, Connelly MA, Drazul D, Klein SM, Favari E, Yancey PG, Williams DL, Rothblat GH. Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL. J Lipid Res. 2001 Dec; 42(12):1969-78.
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Connelly MA, de la Llera-Moya M, Monzo P, Yancey PG, Drazul D, Stoudt G, Fournier N, Klein SM, Rothblat GH, Williams DL. Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI), are localized to the extracellular receptor domain. Biochemistry. 2001 May 01; 40(17):5249-59.
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Yancey PG, de la Llera-Moya M, Swarnakar S, Monzo P, Klein SM, Connelly MA, Johnson WJ, Williams DL, Rothblat GH. High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI. J Biol Chem. 2000 Nov 24; 275(47):36596-604.
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Williams DL, Temel RE, Connelly MA. Roles of scavenger receptor BI and APO A-I in selective uptake of HDL cholesterol by adrenal cells. Endocr Res. 2000 Nov; 26(4):639-51.
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Abumrad NA, Sfeir Z, Connelly MA, Coburn C. Lipid transporters: membrane transport systems for cholesterol and fatty acids. Curr Opin Clin Nutr Metab Care. 2000 Jul; 3(4):255-62.
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Williams DL, de La Llera-Moya M, Thuahnai ST, Lund-Katz S, Connelly MA, Azhar S, Anantharamaiah GM, Phillips MC. Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif. J Biol Chem. 2000 Jun 23; 275(25):18897-904.
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Swarnakar S, Temel RE, Connelly MA, Azhar S, Williams DL. Scavenger receptor class B, type I, mediates selective uptake of low density lipoprotein cholesteryl ester. J Biol Chem. 1999 Oct 15; 274(42):29733-9.
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Williams DL, Connelly MA, Temel RE, Swarnakar S, Phillips MC, de la Llera-Moya M, Rothblat GH. Scavenger receptor BI and cholesterol trafficking. Curr Opin Lipidol. 1999 Aug; 10(4):329-39.
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Connelly MA, Klein SM, Azhar S, Abumrad NA, Williams DL. Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake. J Biol Chem. 1999 Jan 01; 274(1):41-7.
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