 bcl-X Protein
"bcl-X Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.
| Descriptor ID |
D051020
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| MeSH Number(s) |
D12.644.360.075.718.937 D12.776.476.075.718.875
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| Concept/Terms |
bcl-X Protein- bcl-X Protein
- bcl X Protein
- bcl2L1 Protein
- bcl2-Like 1 Protein
- bcl2 Like 1 Protein
bcl-Xbeta Protein- bcl-Xbeta Protein
- bcl Xbeta Protein
- bcl-Xb Protein
- bcl Xb Protein
- bcl-x(beta) Protein
bcl-XS Protein- bcl-XS Protein
- bcl XS Protein
- bcl-Xshort Protein
- bcl Xshort Protein
- bcl-X(S) Protein
bcl-XL Protein- bcl-XL Protein
- bcl XL Protein
- bcl-Xlong Protein
- bcl Xlong Protein
- bcl-X(L) Protein
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Below are MeSH descriptors whose meaning is more general than "bcl-X Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-X Protein".
This graph shows the total number of publications written about "bcl-X Protein" by people in this website by year, and whether "bcl-X Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "bcl-X Protein" by people in Profiles.
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Waibel M, Solomon VS, Knight DA, Ralli RA, Kim SK, Banks KM, Vidacs E, Virely C, Sia KC, Bracken LS, Collins-Underwood R, Drenberg C, Ramsey LB, Meyer SC, Takiguchi M, Dickins RA, Levine R, Ghysdael J, Dawson MA, Lock RB, Mullighan CG, Johnstone RW. Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors. Cell Rep. 2013 Nov 27; 5(4):1047-59.
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Gal AA, Sheppard MN, Nolen JD, Cohen C. p53, cellular proliferation, and apoptosis-related factors in thymic neuroendocrine tumors. Mod Pathol. 2004 Jan; 17(1):33-9.
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