HSP40 Heat-Shock Proteins
"HSP40 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of HSP40 heat shock proteins interacts with HSP70 HEAT-SHOCK PROTEINS. HSP40 heat-shock proteins play a role in regulating the ADENOSINE TRIPHOSPHATASES activity of HSP70 heat-shock proteins.
Descriptor ID |
D050956
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MeSH Number(s) |
D12.776.580.216.292
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Concept/Terms |
HSP40 Heat-Shock Proteins- HSP40 Heat-Shock Proteins
- HSP40 Heat Shock Proteins
- Heat-Shock Proteins, HSP40
- Proteins, HSP40 Heat-Shock
- Heat Shock Protein 40 Family
- Heat-Shock Protein 40
- Heat Shock Protein 40
- HSP40 Proteins
- DnaJ Proteins
- HSP40 Protein Family
- Heat-Shock Proteins 40
- Heat Shock Proteins 40
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Below are MeSH descriptors whose meaning is more general than "HSP40 Heat-Shock Proteins".
Below are MeSH descriptors whose meaning is more specific than "HSP40 Heat-Shock Proteins".
This graph shows the total number of publications written about "HSP40 Heat-Shock Proteins" by people in this website by year, and whether "HSP40 Heat-Shock Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 1 | 2 | 2016 | 1 | 0 | 1 | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "HSP40 Heat-Shock Proteins" by people in Profiles.
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Kaida A, Iwakuma T. Regulation of p53 and Cancer Signaling by Heat Shock Protein 40/J-Domain Protein Family Members. Int J Mol Sci. 2021 Dec 16; 22(24).
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Kaida A, Yamamoto S, Parrales A, Young ED, Ranjan A, Alalem MA, Morita KI, Oikawa Y, Harada H, Ikeda T, Thomas SM, Diaz FJ, Iwakuma T. DNAJA1 promotes cancer metastasis through interaction with mutant p53. Oncogene. 2021 08; 40(31):5013-5025.
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Parrales A, Ranjan A, Iyer SV, Padhye S, Weir SJ, Roy A, Iwakuma T. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016 Nov; 18(11):1233-1243.
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Lim II, Farber BA, LaQuaglia MP. Advances in fibrolamellar hepatocellular carcinoma: a review. Eur J Pediatr Surg. 2014 Dec; 24(6):461-6.
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Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, Gleason CE, Murphy JM, Rosenberg BR, Teegan L, Takacs CN, Botero S, Belote R, Germer S, Emde AK, Vacic V, Bhanot U, LaQuaglia MP, Simon SM. Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma. Science. 2014 Feb 28; 343(6174):1010-4.
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