Self-renewal versus transformation: Fbxw7 deletion leads to stem cell activation and leukemogenesis.

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Self-renewal versus transformation: Fbxw7 deletion leads to stem cell activation and leukemogenesis.

Perry JM, Li L. Self-renewal versus transformation: Fbxw7 deletion leads to stem cell activation and leukemogenesis. Genes Dev. 2008 May 01; 22(9):1107-9.

View in: PubMed

subject areas

Animals
Apoptosis
Cell Cycle Proteins
Cell Transformation, Neoplastic
F-Box Proteins
Gene Deletion
Hematopoietic Stem Cells
Humans
Leukemia
Models, Biological
Mutation
Tumor Suppressor Protein p53
Ubiquitin-Protein Ligases

authors with profiles

John M. Perry