Receptor, PAR-2
"Receptor, PAR-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence.
Descriptor ID |
D044464
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MeSH Number(s) |
D12.776.543.750.100.035 D12.776.543.750.792.249
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Concept/Terms |
Receptor, PAR-2- Receptor, PAR-2
- Receptor, PAR 2
- Proteinase Activated Receptor 2
- Receptor, Trypsin
- PAR2 Receptor
- Receptor, PAR2
- Trypsin Receptors
- Receptors, Trypsin
- PAR-2 Receptor
- PAR 2 Receptor
- Protease-Activated Receptor 2
- Protease Activated Receptor 2
- Receptor 2, Protease-Activated
- Trypsin Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptor, PAR-2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, PAR-2".
This graph shows the total number of publications written about "Receptor, PAR-2" by people in this website by year, and whether "Receptor, PAR-2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, PAR-2" by people in Profiles.
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Ramsey LB, Pounds S, Cheng C, Cao X, Yang W, Smith C, Karol SE, Liu C, Panetta JC, Inaba H, Rubnitz JE, Metzger ML, Ribeiro RC, Sandlund JT, Jeha S, Pui CH, Evans WE, Relling MV. Genetics of pleiotropic effects of dexamethasone. Pharmacogenet Genomics. 2017 08; 27(8):294-302.
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