 Neuropilin-1
"Neuropilin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and axonal guidance. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS, and binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
| Descriptor ID |
D039942
|
| MeSH Number(s) |
D12.776.543.750.055.500
|
| Concept/Terms |
Neuropilin-1- Neuropilin-1
- Neuropilin 1
- NRP1 Protein
- Semaphorin III Receptor
- A5 Antigen
- Antigen, A5
- Npn-1 Protein
- Npn 1 Protein
- Sema III Receptor
- Receptor, Sema III
|
Below are MeSH descriptors whose meaning is more general than "Neuropilin-1".
Below are MeSH descriptors whose meaning is more specific than "Neuropilin-1".
This graph shows the total number of publications written about "Neuropilin-1" by people in this website by year, and whether "Neuropilin-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Neuropilin-1" by people in Profiles.
-
Maulik D, De A, Ragolia L, Evans J, Grigoryev D, Lankachandra K, Mundy D, Muscat J, Gerkovich MM, Ye SQ. Down-regulation of placental neuropilin-1 in fetal growth restriction. Am J Obstet Gynecol. 2016 Feb; 214(2):279.e1-279.e9.
-
McLennan R, Kulesa PM. Neuropilin-1 interacts with the second branchial arch microenvironment to mediate chick neural crest cell dynamics. Dev Dyn. 2010 Jun; 239(6):1664-73.
-
McLennan R, Kulesa PM. In vivo analysis reveals a critical role for neuropilin-1 in cranial neural crest cell migration in chick. Dev Biol. 2007 Jan 01; 301(1):227-39.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|