Calcimycin
"Calcimycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
Descriptor ID |
D000001
|
MeSH Number(s) |
D03.438.221.173
|
Concept/Terms |
A-23187- A-23187
- A 23187
- Antibiotic A23187
- A23187, Antibiotic
- A23187
|
Below are MeSH descriptors whose meaning is more general than "Calcimycin".
Below are MeSH descriptors whose meaning is more specific than "Calcimycin".
This graph shows the total number of publications written about "Calcimycin" by people in this website by year, and whether "Calcimycin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Calcimycin" by people in Profiles.
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Franza BR, Rauscher FJ, Josephs SF, Curran T. The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites. Science. 1988 Mar 04; 239(4844):1150-3.
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Pompidou A, Corral M, Michel P, Defer N, Kruh J, Curran T. The effects of phorbol ester and Ca ionophore on c-fos and c-myc expression and on DNA synthesis in human lymphocytes are not directly related. Biochem Biophys Res Commun. 1987 Oct 14; 148(1):435-42.
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Pompidou A, Corral M, Michel P, Kruh J, Curran T. [Stimulation of human lymphocytes by phorbol acetate and a calcium ionophore induces an early transient expression of the c-fos oncogene followed by c-myc]. C R Acad Sci III. 1986; 303(11):445-7.
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Bravo R, Burckhardt J, Curran T, M?ller R. Stimulation and inhibition of growth by EGF in different A431 cell clones is accompanied by the rapid induction of c-fos and c-myc proto-oncogenes. EMBO J. 1985 May; 4(5):1193-7.
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Curran T, Bravo R, M?ller R. Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation. Cancer Surv. 1985; 4(4):655-81.