A form of stimulus sensitive myoclonic epilepsy inherited as an autosomal recessive condition. The most common presenting feature is a single seizure in the second decade of life. This is followed by progressive myoclonus, myoclonic seizures, tonic-clonic seizures, focal occipital seizures, intellectual decline, and severe motor and coordination impairments. Most affected individuals do not live past the age of 25 years. Concentric amyloid (Lafora) bodies are found in neurons, liver, skin, bone, and muscle (From Menkes, Textbook of Childhood Neurology, 5th ed, pp111-110)

Descriptor ID	D020192
MeSH Number(s)	C10.228.140.490.250.650.500 C10.574.500.529 C16.320.400.480
Concept/Terms	Lafora Disease Lafora Disease Disease, Lafora Epilepsy, Progressive Myoclonic, Lafora Lafora Body Disease Disease, Lafora Body Lafora Body Disorder Disorder, Lafora Body Lafora Progressive Myoclonic Epilepsy Epilepsy, Progressive Myoclonic 2A Lafora Type Progressive Myoclonic Epilepsy Myoclonic Epilepsy of Lafora Lafora Myoclonic Epilepsy Progressive Myoclonic Epilepsy Type 2 Progressive Myoclonic Epilepsy, Lafora Progressive Myoclonic Epilepsy, Lafora Type Progressive Myoclonus Epilepsy, Lafora Type Epilepsy Progressive Myoclonic 2 Lafora Progressive Myoclonus Epilepsy Lafora Body Disease, Late Onset Lafora Body Disease, Late Onset Late Onset Lafora Body Disease Lafora-Body Disease, Late Onset

Below are MeSH descriptors whose meaning is more general than "Lafora Disease".

Below are MeSH descriptors whose meaning is related to "Lafora Disease".

Below are MeSH descriptors whose meaning is more specific than "Lafora Disease".