Hyperhomocysteinemia
"Hyperhomocysteinemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 μmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.
Descriptor ID |
D020138
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MeSH Number(s) |
C16.320.565.100.480 C18.452.603.378 C18.452.648.100.480 C18.654.521.500.133.699.418
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hyperhomocysteinemia".
Below are MeSH descriptors whose meaning is more specific than "Hyperhomocysteinemia".
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