 2,3-Diphosphoglycerate
"2,3-Diphosphoglycerate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
| Descriptor ID |
D019794
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| MeSH Number(s) |
D02.241.081.844.387.388.175 D02.241.511.902.387.388.175 D02.705.400.140.175 D09.811.366.388.175
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| Concept/Terms |
2,3-Diphosphoglycerate- 2,3-Diphosphoglycerate
- 2,3 Diphosphoglycerate
- 2,3-DPG
- Glycerate 2,3-Bisphosphate
- 2,3-Bisphosphate, Glycerate
- 2,3-Bisphosphoglycerate
- 2,3 Bisphosphoglycerate
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