 Phosphatidylinositol 4,5-Diphosphate
"Phosphatidylinositol 4,5-Diphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019269
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| MeSH Number(s) |
D10.570.755.375.760.400.942.625.900
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| Concept/Terms |
Phosphatidylinositol 4,5-Diphosphate- Phosphatidylinositol 4,5-Diphosphate
- 4,5-Diphosphate, Phosphatidylinositol
- Phosphatidylinositol 4,5 Diphosphate
- Phosphatidylinositol Phosphate, PtdIns(4,5)P2
- PtIns 4,5-P2
- PtdIns(4,5)P2
- PtdInsP
- PtdInsP2
- Phosphatidylinositol 4,5-Biphosphate
- 4,5-Biphosphate, Phosphatidylinositol
- Phosphatidylinositol 4,5 Biphosphate
- Phosphatidylinositol-4,5-Biphosphate
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol 4,5-Diphosphate".
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Below are the most recent publications written about "Phosphatidylinositol 4,5-Diphosphate" by people in Profiles.
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Yun M, Keshvara L, Park CG, Zhang YM, Dickerson JB, Zheng J, Rock CO, Curran T, Park HW. Crystal structures of the Dab homology domains of mouse disabled 1 and 2. J Biol Chem. 2003 Sep 19; 278(38):36572-81.
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