Receptor, IGF Type 1
"Receptor, IGF Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.
Descriptor ID |
D017526
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MeSH Number(s) |
D08.811.913.696.620.682.725.400.185 D12.776.543.750.060.468 D12.776.543.750.750.400.780.400
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Concept/Terms |
Receptor, IGF Type 1- Receptor, IGF Type 1
- IGF-1 Receptor
- IGF 1 Receptor
- Receptor, IGF-1
- IGF-I Receptor
- IGF I Receptor
- Receptors, Insulin-Like-Growth Factor I
- Receptor, IGF-I
- Receptor, IGF I
- Receptor, Insulin-Like Growth Factor I
- Receptor, Insulin-Like Growth Factor Type 1
- Receptors, IGF-1
- IGF-1 Receptors
- Receptors, IGF 1
- IGF Type 1 Receptor
- Insulin-Like-Growth Factor I Receptor
- Insulin Like Growth Factor I Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptor, IGF Type 1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, IGF Type 1".
This graph shows the total number of publications written about "Receptor, IGF Type 1" by people in this website by year, and whether "Receptor, IGF Type 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptor, IGF Type 1" by people in Profiles.
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Wu S, Yang W, De Luca F. Insulin-Like Growth Factor-Independent Effects of Growth Hormone on Growth Plate Chondrogenesis and Longitudinal Bone Growth. Endocrinology. 2015 Jul; 156(7):2541-51.
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Venkatraman A, He XC, Thorvaldsen JL, Sugimura R, Perry JM, Tao F, Zhao M, Christenson MK, Sanchez R, Yu JY, Peng L, Haug JS, Paulson A, Li H, Zhong XB, Clemens TL, Bartolomei MS, Li L. Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence. Nature. 2013 Aug 15; 500(7462):345-9.
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Reid-Lombardo KM, Fridley BL, Bamlet WR, Cunningham JM, Sarr MG, Petersen GM. Survival is associated with genetic variation in inflammatory pathway genes among patients with resected and unresected pancreatic cancer. Ann Surg. 2013 Jun; 257(6):1096-102.
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Wu S, Aguilar AL, Ostrow V, De Luca F. Insulin resistance secondary to a high-fat diet stimulates longitudinal bone growth and growth plate chondrogenesis in mice. Endocrinology. 2011 Feb; 152(2):468-75.
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