A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)

Descriptor ID	D017246
MeSH Number(s)	C05.651.460.700 C10.292.562.750.250 C10.597.622.447.511 C10.668.491.500.700 C11.590.472.250 C18.452.660.560.700 C23.888.592.636.447.511
Concept/Terms	Ophthalmoplegia, Chronic Progressive External Ophthalmoplegia, Chronic Progressive External Graefe Disease Disease, Graefe Mitochondrial Ocular Myopathy Myopathy, Mitochondrial Ocular Ocular Myopathy, Mitochondrial Chronic Progressive External Ophthalmoplegia Graefe's Disease Ocular Myopathy of Von Graefe-Fuchs Ocular Myopathy of Von Graefe Fuchs Ophthalmoplegia, Progressive External External Ophthalmoplegia, Progressive Progressive External Ophthalmoplegia CPEO Ocular Muscular Dystrophy Dystrophy, Ocular Muscular Muscular Dystrophies, Ocular Muscular Dystrophy, Ocular Ocular Muscular Dystrophies

Below are MeSH descriptors whose meaning is more general than "Ophthalmoplegia, Chronic Progressive External".

Below are MeSH descriptors whose meaning is related to "Ophthalmoplegia, Chronic Progressive External".

Below are MeSH descriptors whose meaning is more specific than "Ophthalmoplegia, Chronic Progressive External".