 Fibroblast Growth Factor 1
"Fibroblast Growth Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
| Descriptor ID |
D016220
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| MeSH Number(s) |
D12.644.276.624.110 D12.776.467.624.110 D23.529.624.110
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| Concept/Terms |
Fibroblast Growth Factor 1- Fibroblast Growth Factor 1
- HBGF-1
- Heparin-Binding Fibroblast Growth Factor Class I
- Heparin-Binding Growth Factor, Class I
- Heparin Binding Growth Factor, Class I
- Fibroblast Growth Factor, Acidic
- Fibroblast Growth Factor-1
- Class I Heparin-Binding Growth Factor
- FGF-1
- FGF1
- Acidic Fibroblast Growth Factor
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Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factor 1".
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This graph shows the total number of publications written about "Fibroblast Growth Factor 1" by people in this website by year, and whether "Fibroblast Growth Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibroblast Growth Factor 1" by people in Profiles.
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Zhao M, Perry JM, Marshall H, Venkatraman A, Qian P, He XC, Ahamed J, Li L. Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells. Nat Med. 2014 Nov; 20(11):1321-6.
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Kurimchak A, Haines DS, Garriga J, Wu S, De Luca F, Sweredoski MJ, Deshaies RJ, Hess S, Gra?a X. Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55a holoenzyme. Mol Cell Biol. 2013 Aug; 33(16):3330-42.
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