Pentostatin
"Pentostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Descriptor ID |
D015649
|
MeSH Number(s) |
D03.383.742.680.350.200.700 D13.570.230.677 D13.570.685.350.200.700
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Concept/Terms |
Pentostatin- Pentostatin
- Co-Vidarabine
- Co Vidarabine
- Deoxycoformycin
- 2'-Deoxycoformycin
- 2' Deoxycoformycin
Nipent- Nipent
- Wyeth Brand of Pentostatin
- Supergen Brand of Pentostatin
- Warner-Lambert Brand of Pentostatin
- Lederle Brand of Pentostatin
- Prasfarma Brand of Pentostatin
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Below are MeSH descriptors whose meaning is more general than "Pentostatin".
Below are MeSH descriptors whose meaning is more specific than "Pentostatin".
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Below are the most recent publications written about "Pentostatin" by people in Profiles.
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Lowenthal RM, Wiley JS, Rooney KF, Challis DR, Woods GM. Lennert's lymphoma: response to 2'-deoxycoformycin. Br J Haematol. 1990 Dec; 76(4):555-6.