 Oligonucleotide Probes
"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
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| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
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Farooqi MS, Mitui M, Londin ER, Park JY. High Concentration Capture Probes Enhance Massively Parallel Sequencing Assays. Clin Chem. 2016 07; 62(7):1032-4.
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Selvaraju SB, Wurst M, Horvat RT, Selvarangan R. Evaluation of three analyte-specific reagents for detection and typing of herpes simplex virus in cerebrospinal fluid. Diagn Microbiol Infect Dis. 2009 Mar; 63(3):286-91.
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Selvarangan R, Bui U, Limaye AP, Cookson BT. Rapid identification of commonly encountered Candida species directly from blood culture bottles. J Clin Microbiol. 2003 Dec; 41(12):5660-4.
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Pastinen T, Kurg A, Metspalu A, Peltonen L, Syv?nen AC. Minisequencing: a specific tool for DNA analysis and diagnostics on oligonucleotide arrays. Genome Res. 1997 Jun; 7(6):606-14.
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Karges WJ, Gaedigk R, Dosch HM. Quantitative analysis of gene expression in different tissues by template-calibrated RT-PCR and laser-induced fluorescence. PCR Methods Appl. 1994 Dec; 4(3):154-9.
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Xanthoudakis S, Curran T. Analysis of c-Fos and c-Jun redox-dependent DNA binding activity. Methods Enzymol. 1994; 234:163-74.
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Kerppola TK, Curran T. Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity. Cell. 1991 Jul 26; 66(2):317-26.
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Gius D, Cao XM, Rauscher FJ, Cohen DR, Curran T, Sukhatme VP. Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements. Mol Cell Biol. 1990 Aug; 10(8):4243-55.
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Macgregor PF, Abate C, Curran T. Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1. Oncogene. 1990 Apr; 5(4):451-8.
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