Tunicamycin
"Tunicamycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.
| Descriptor ID |
D014415
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| MeSH Number(s) |
D03.383.742.680.725 D13.570.685.725
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tunicamycin".
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Below are the most recent publications written about "Tunicamycin" by people in Profiles.
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Xu D, Perez RE, Rezaiekhaligh MH, Bourdi M, Truog WE. Knockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis. Am J Physiol Lung Cell Mol Physiol. 2009 Jul; 297(1):L44-51.