Thalidomide

"Thalidomide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.

Descriptor ID	D013792
MeSH Number(s)	D02.241.223.805.810.800 D03.383.621.808.800 D03.438.513.750.750
Concept/Terms	Thalidomide Thalidomide Sedoval Sedoval Thalomid Thalomid Celgene Brand of Thalidomide

Below are MeSH descriptors whose meaning is more general than "Thalidomide".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Carbocyclic [D02.241.223]
Phthalic Acids [D02.241.223.805]
Phthalimides [D02.241.223.805.810]
Thalidomide [D02.241.223.805.810.800]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Piperidines [D03.383.621]
Piperidones [D03.383.621.808]
Thalidomide [D03.383.621.808.800]
Heterocyclic Compounds, 2-Ring [D03.438]
Isoindoles [D03.438.513]
Phthalimides [D03.438.513.750]
Thalidomide [D03.438.513.750.750]

Below are MeSH descriptors whose meaning is related to "Thalidomide".

Below are MeSH descriptors whose meaning is more specific than "Thalidomide".

publications

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