 Growth Hormone
"Growth Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
| Descriptor ID |
D013006
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| MeSH Number(s) |
D06.472.699.631.525.425 D12.644.548.691.525.425
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| Concept/Terms |
Growth Hormone- Growth Hormone
- Pituitary Growth Hormone
- Somatotropin
- Growth Hormone, Pituitary
Growth Hormone, Recombinant- Growth Hormone, Recombinant
- Pituitary Growth Hormones, Recombinant
- Recombinant Pituitary Growth Hormones
- Recombinant Growth Hormones
- Growth Hormones, Recombinant
- Recombinant Growth Hormone
- Somatotropins, Recombinant
- Somatotropin, Recombinant
- Recombinant Somatotropin
- Growth Hormones Pituitary, Recombinant
- Recombinant Somatotropins
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Below are MeSH descriptors whose meaning is more general than "Growth Hormone".
Below are MeSH descriptors whose meaning is more specific than "Growth Hormone".
This graph shows the total number of publications written about "Growth Hormone" by people in this website by year, and whether "Growth Hormone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Growth Hormone" by people in Profiles.
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De Luca F. Regulatory role of NF-?B in growth plate chondrogenesis and its functional interaction with Growth Hormone. Mol Cell Endocrinol. 2020 08 20; 514:110916.
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De Luca F. Regulatory Role for Growth Hormone in Statural Growth: IGF-Dependent and IGF-Independent Effects on Growth Plate Chondrogenesis and Longitudinal Bone Growth. Pediatr Endocrinol Rev. 2018 Sep; 16(Suppl 1):33-38.
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De Luca F. Role of Nuclear Factor Kappa B (NF-?B) in Growth Plate Chondrogenesis. Pediatr Endocrinol Rev. 2016 Jun; 13(4):720-30.
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Wu S, Yang W, De Luca F. Insulin-Like Growth Factor-Independent Effects of Growth Hormone on Growth Plate Chondrogenesis and Longitudinal Bone Growth. Endocrinology. 2015 Jul; 156(7):2541-51.
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Grunwald T, De Luca F. Role of Fibroblast Growth Factor 21 (FGF21) in the Regulation of Statural Growth. Curr Pediatr Rev. 2015; 11(2):98-105.
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Wu S, Grunwald T, Kharitonenkov A, Dam J, Jockers R, De Luca F. Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing leptin receptor overlapping transcript (LEPROT) and leptin receptor overlapping transcript-like 1 (LEPROTL1) expression. J Biol Chem. 2013 Sep 20; 288(38):27375-27383.
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Wu S, Levenson A, Kharitonenkov A, De Luca F. Fibroblast growth factor 21 (FGF21) inhibits chondrocyte function and growth hormone action directly at the growth plate. J Biol Chem. 2012 Jul 27; 287(31):26060-7.
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Kubicky RA, Wu S, Kharitonenkov A, De Luca F. Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice. Endocrinology. 2012 May; 153(5):2287-95.
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Wu S, Morrison A, Sun H, De Luca F. Nuclear factor-kappaB (NF-kappaB) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2. J Biol Chem. 2011 Jul 15; 286(28):24726-34.
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Kennedy MJ, Davis DA, Smith N, Gaedigk A, Pearce RE, Kearns GL. Reduced activities of cytochrome P450 1A2 and xanthine oxidase in children with growth hormone deficiency. Clin Pharmacol Ther. 2008 Dec; 84(6):674-8.
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