Pentylenetetrazole
"Pentylenetetrazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
| Descriptor ID |
D010433
|
| MeSH Number(s) |
D03.383.066.600
|
| Concept/Terms |
Pentylenetetrazole- Pentylenetetrazole
- Pentylenetetrazol
- Pentetrazole
- Leptazole
- Pentamethylenetetrazole
Corasol- Corasol
- Corazole
- Korazole
- Corazol
- Korazol
|
Below are MeSH descriptors whose meaning is more general than "Pentylenetetrazole".
Below are MeSH descriptors whose meaning is more specific than "Pentylenetetrazole".
This graph shows the total number of publications written about "Pentylenetetrazole" by people in this website by year, and whether "Pentylenetetrazole" was a major or minor topic of these publications.
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Below are the most recent publications written about "Pentylenetetrazole" by people in Profiles.
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Kasof GM, Mandelzys A, Maika SD, Hammer RE, Curran T, Morgan JI. Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J Neurosci. 1995 Jun; 15(6):4238-49.
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Sonnenberg JL, Mitchelmore C, Macgregor-Leon PF, Hempstead J, Morgan JI, Curran T. Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain. J Neurosci Res. 1989 Sep; 24(1):72-80.
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Sonnenberg JL, Macgregor-Leon PF, Curran T, Morgan JI. Dynamic alterations occur in the levels and composition of transcription factor AP-1 complexes after seizure. Neuron. 1989 Sep; 3(3):359-65.
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Morgan JI, Cohen DR, Hempstead JL, Curran T. Mapping patterns of c-fos expression in the central nervous system after seizure. Science. 1987 Jul 10; 237(4811):192-7.