Novobiocin
"Novobiocin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
Descriptor ID |
D009675
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MeSH Number(s) |
D03.383.663.283.446.139.500 D03.438.150.446.139.500 D09.408.554
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Concept/Terms |
Novobiocin- Novobiocin
- Streptonivicin
- Crystallinic Acid
Novobiocin Sodium- Novobiocin Sodium
- Sodium, Novobiocin
- Novobiocin, Monosodium Salt
- Monosodium Salt Novobiocin
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Below are MeSH descriptors whose meaning is more general than "Novobiocin".
Below are MeSH descriptors whose meaning is more specific than "Novobiocin".
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Below are the most recent publications written about "Novobiocin" by people in Profiles.
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Heruth DP, Wetmore LA, Leyva A, Rothberg PG. Influence of protein tyrosine phosphorylation on the expression of the c-myc oncogene in cancer of the large bowel. J Cell Biochem. 1995 May; 58(1):83-94.