Kininogens
"Kininogens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
Descriptor ID |
D007704
|
MeSH Number(s) |
D12.644.276.812.654 D12.776.124.125.635 D12.776.467.812.654 D12.776.811.420 D23.119.630 D23.469.050.375.425 D23.529.812.654
|
Concept/Terms |
Kininogens- Kininogens
- Prokinins
- Prekinins
- Cystatins, Kininogen
- Kininogen Cystatins
|
Below are MeSH descriptors whose meaning is more general than "Kininogens".
Below are MeSH descriptors whose meaning is more specific than "Kininogens".
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